Daf-2 抗体 (C-Term)
This anti-Daf-2 antibody is a 兔 多克隆 antibody detecting Daf-2 in IHC. Suitable for C. elegans.
Quick Overview for Daf-2 抗体 (C-Term) (ABIN965970)
抗原
See all Daf-2 (DAF2) products
Daf-2 (DAF2)
(Decay Accelerating Factor 2 (DAF2))
适用
C. elegans
宿主
兔
克隆类型
多克隆
应用范围
Immunohistochemistry (IHC)
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抗原表位
- C-Term
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Caenorhabditis elegans daf-2(Abnormal dauer formation protein 2)
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))
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别名
- Daf-2
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背景
- The daf-2 is an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. A C. elegans neurosecretory signaling system regulates whether animals enter the reproductive life cycle or arrest development at the long-lived dauer diapause stage. daf-2, a key gene in the genetic pathway that mediates this endocrine signaling, encodes an insulin receptor family member. Decreases in DAF-2 signaling induce metabolic and developmental changes, as in mammalian metabolic control by the insulin receptor. Decreased DAF-2 signaling also causes an increase in life-span. Lifespan regulation by insulin-like metabolic control is analogous to mammalian longevity enhancement induced by caloric restriction, suggesting a general link between metabolism, diapause, and longevity.
抗原
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