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Daf-2 抗体 (C-Term)

The 兔 多克隆 anti-Daf-2 antibody (ABIN965970) specifically detects Daf-2 in IHC. The antibody is reactive with C. elegans samples.
产品编号 ABIN965970
发货至: 中国
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Quick Overview for Daf-2 抗体 (C-Term) (ABIN965970)

抗原

See all Daf-2 (DAF2) products
Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))

适用

C. elegans

宿主

克隆类型

多克隆

应用范围

Immunohistochemistry (IHC)
  • 抗原表位

    C-Term

    纯化方法

    Purified by antigen-specific affinity chromatography.

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Caenorhabditis elegans daf-2(Abnormal dauer formation protein 2)
  • 应用备注

    ELISA, Western blotting: 1µg/ml for 2hrs.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    This antibody is stored in PBS, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))

    别名

    Daf-2

    背景

    The daf-2 is an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. A C. elegans neurosecretory signaling system regulates whether animals enter the reproductive life cycle or arrest development at the long-lived dauer diapause stage. daf-2, a key gene in the genetic pathway that mediates this endocrine signaling, encodes an insulin receptor family member. Decreases in DAF-2 signaling induce metabolic and developmental changes, as in mammalian metabolic control by the insulin receptor. Decreased DAF-2 signaling also causes an increase in life-span. Lifespan regulation by insulin-like metabolic control is analogous to mammalian longevity enhancement induced by caloric restriction, suggesting a general link between metabolism, diapause, and longevity.
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