Protein 1A functions as a suppressor of RNA-mediated gene silencing, an antiviral defense mechanism of insect cells. Binds to long dsRNA and to a lesser extent, to siRNA. RNA-directed RNA polymerase replicates genomic and antigenomic RNA.
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Johnson, Christian: "The novel genome organization of the insect picorna-like virus Drosophila C virus suggests this virus belongs to a previously undescribed virus family." in: The Journal of general virology, Vol. 79 ( Pt 1), pp. 191-203, (1998) (PubMed).