DCK 抗体
(Deoxycytidine Kinase (DCK))
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008].
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Latest Publications for our DCK 抗体
: "Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity." in: BMC cancer, Vol. 18, Issue 1, pp. 466, (2018) (PubMed).: "Prognostic effect of hENT1, dCK and HuR expression by morphological type in periampullary adenocarcinoma, including pancreatic cancer." in: Acta oncologica (Stockholm, Sweden), Vol. 55, Issue 3, pp. 286-96, (2016) (PubMed).
: "The effects of forodesine in murine and human multiple myeloma cells." in: Advances in hematology, Vol. 2010, pp. 131895, (2010) (PubMed).
: "Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity." in: Blood, Vol. 113, Issue 10, pp. 2145-53, (2009) (PubMed).
: "The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase." in: Cancer research, Vol. 69, Issue 11, pp. 4567-72, (2009) (PubMed).
: "Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 88, Issue 7, pp. 773-84, (2008) (PubMed).
: "Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants." in: The Journal of pharmacology and experimental therapeutics, Vol. 323, Issue 3, pp. 935-45, (2007) (PubMed).
: "Molecular basis of 2',3'-dideoxycytidine-induced drug resistance in human cells." in: Molecular and cellular biochemistry, Vol. 231, Issue 1-2, pp. 173-7, (2002) (PubMed).
Aliases for DCK 抗体
deoxycytidine kinase (DCK) 抗体deoxycytidine kinase (dck) 抗体
deoxycytidine kinase, gene 2 L homeolog (dck.2.L) 抗体
deoxycytidine kinase, gene 2 (dck.2) 抗体
deoxycytidine kinase (Dck) 抗体
Deoxycytidine kinase (FPV059) 抗体
Deoxycytidine kinase (FPV151) 抗体
deoxycytidine kinase, gene 1 L homeolog (dck.1.L) 抗体
dck 抗体
DCK 抗体
dck1 抗体
wu:fc15f06 抗体
zgc:101771 抗体
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