DCC 抗体
(Deleted in Colorectal Carcinoma (DCC))
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009].
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Latest Publications for our DCC 抗体
: "Progesterone down-regulates SLIT/ROBO expression in mouse corpus luteum." in: Acta histochemica, Vol. 119, Issue 7, pp. 740-746, (2017) (PubMed).
: "Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain." in: The Journal of comparative neurology, Vol. 520, Issue 16, pp. 3650-72, (2012) (PubMed).
: "The DCC protein and prognosis in colorectal cancer." in: The New England journal of medicine, Vol. 335, Issue 23, pp. 1727-32, (1996) (PubMed).
: "Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues." in: Cancer research, Vol. 54, Issue 16, pp. 4493-501, (1994) (PubMed).
: "Identification of a chromosome 18q gene that is altered in colorectal cancers." in: Science (New York, N.Y.), Vol. 247, Issue 4938, pp. 49-56, (1990) (PubMed).
: "Genetic alterations during colorectal-tumor development." in: The New England journal of medicine, Vol. 319, Issue 9, pp. 525-32, (1988) (PubMed).
: "Clonal analysis of human colorectal tumors." in: Science (New York, N.Y.), Vol. 238, Issue 4824, pp. 193-7, (1987) (PubMed).
: "Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain." in: The Journal of comparative neurology, Vol. 520, Issue 16, pp. 3650-72, (2012) (PubMed).
: "The DCC protein and prognosis in colorectal cancer." in: The New England journal of medicine, Vol. 335, Issue 23, pp. 1727-32, (1996) (PubMed).
: "Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues." in: Cancer research, Vol. 54, Issue 16, pp. 4493-501, (1994) (PubMed).
: "Identification of a chromosome 18q gene that is altered in colorectal cancers." in: Science (New York, N.Y.), Vol. 247, Issue 4938, pp. 49-56, (1990) (PubMed).
: "Genetic alterations during colorectal-tumor development." in: The New England journal of medicine, Vol. 319, Issue 9, pp. 525-32, (1988) (PubMed).
: "Clonal analysis of human colorectal tumors." in: Science (New York, N.Y.), Vol. 238, Issue 4824, pp. 193-7, (1987) (PubMed).
Aliases for DCC 抗体
DCC netrin 1 receptor (DCC) 抗体DCC netrin 1 receptor (dcc) 抗体
deleted in colorectal carcinoma (Dcc) 抗体
deleted in colorectal carcinoma (dcc) 抗体
DCC netrin 1 receptor (Dcc) 抗体
netrin receptor DCC (LOC100712666) 抗体
C030036D22Rik 抗体
CRC18 抗体
CRCR1 抗体
DCC 抗体
Dcc 抗体
dcca-A 抗体
IGDCC1 抗体
Igdcc1 抗体
MRMV1 抗体
xdcc 抗体
XDCCa 抗体
zdcc 抗体
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