(Cytochrome P450, Family 2, Subfamily S, Polypeptide 1 (CYP2S1))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens\; however, the specific function of the human protein has not been determined. [provided by RefSeq, Jul 2008].
Yang, Zhou, Li, Tong, Sun, Qing, Sun, Yang, Hu, Jiang, Yan, He, Wan: "Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines." in: Scientific reports, Vol. 6, pp. 33078, (2016) (PubMed).
Yang, Li, Li, Tong, Hu, Yang, Yan, He, Wan: "CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of ?-catenin signaling." in: Experimental cell research, Vol. 331, Issue 2, pp. 377-86, (2015) (PubMed).
Aliases for CYP2S1 抗体
cytochrome P450, family 2, subfamily s, polypeptide 1 (Cyp2s1) 抗体 cytochrome P450 family 2 subfamily S member 1 (CYP2S1) 抗体 1200011C15Rik 抗体 AU041727 抗体 C79779 抗体