CYP2F2 蛋白
(Cytochrome P450, Family 2, Subfamily F, Polypeptide 2 (CYP2F2))
Involved in the regio- and stereoselective transformation of naphthalene to trans-1R-hydroxy-2R-glutathionyl- 1,2-dihydronaphthalene in the presence of glutathione and glutathione S-transferases. It specifically catalyzes the production of a very reactive and potentially toxic intermediate, the 2R,2S arene oxide, that is associated with necrosis of the unciliated bronchiolar epithelial cells or Clara cells in lung.
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Recommended CYP2F2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3133767
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7423522
Quantity
100 μg
Datasheet
Datasheet
Synonyms and alternative names related to CYP2F2
cytochrome P450, family 2, subfamily f, polypeptide 2 (Cyp2f2), Cyp2fProtein level used designations for CYP2F2
- CYPIIF2
- cytochrome P450 2F2
- cytochrome P450, 2f2
- cytochrome P450-NAH-2
- naphthalene dehydrogenase
- naphthalene hydroxylase
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