CYP2C9 抗体
(Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008].
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35 results
CYP2C9
适用: 人
WB
宿主: 小鼠
Monoclonal
682CT5-6-2
unconjugated
1 image
3 references
Latest Publications for our CYP2C9 抗体
: "Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation." in: Oncotarget, Vol. 8, Issue 9, pp. 15377-15392, (2017) (PubMed).: "A novel mouse model for stable engraftment of a human immune system and human hepatocytes." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119820, (2015) (PubMed).
: "Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Mongolian population in China." in: Genetics and molecular research : GMR, Vol. 9, Issue 3, pp. 1844-51, (2010) (PubMed).
: "The association of protein S Tokushima-K196E with a risk of deep vein thrombosis." in: International journal of hematology, Vol. 92, Issue 2, pp. 302-5, (2010) (PubMed).
: "New genetic variant that might improve warfarin dose prediction in African Americans." in: British journal of clinical pharmacology, Vol. 70, Issue 3, pp. 393-9, (2010) (PubMed).
: "Production of inhibitory polyclonal antibodies against cytochrome P450s." in: Drug metabolism and pharmacokinetics, Vol. 18, Issue 3, pp. 163-72, (2004) (PubMed).
: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).
Aliases for CYP2C9 抗体
cytochrome P450 family 2 subfamily C member 9 (CYP2C9) 抗体CPC9 抗体
CYP2C 抗体
CYP2C10 抗体
CYPIIC9 抗体
P450IIC9 抗体
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