(Cytochrome P450, Family 2, Subfamily A, Polypeptide 13 (CYP2A13))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008].
Fagerberg, Hallström, Oksvold, Kampf, Djureinovic, Odeberg, Habuka, Tahmasebpoor, Danielsson, Edlund, Asplund, Sjöstedt, Lundberg, Szigyarto, Skogs, Takanen, Berling, Tegel, Mulder, Nilsson, Schwenk et al.: "Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. ..." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 2, pp. 397-406, (2014) (PubMed).
Goto, Moriuchi, Fu, Ikegawa, Matsubara, Chang, Uno, Morigaki, Isshiki, Imaishi: "The effects of single nucleotide polymorphisms in CYP2A13 on metabolism of 5-methoxypsoralen." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 38, Issue 12, pp. 2110-6, (2010) (PubMed).
Aliases for CYP2A13 抗体
cytochrome P450 family 2 subfamily A member 13 (CYP2A13) 抗体 cytochrome P450, family 2, subfamily A, polypeptide 13 (CYP2A13) 抗体 cytochrome P450 family 2 subfamily A member 13 L homeolog (cyp2a13.L) 抗体 cytochrome P450 family 2 subfamily A member 13 (cyp2a13) 抗体 cytochrome P450 family 2 subfamily A polypeptide 13 (CYP2A13) 抗体 cytochrome P450 2A13 (LOC540707) 抗体 CPAD 抗体 CYP2A 抗体 CYP2A6 抗体 CYP2A13 抗体 CYPIIA13 抗体 MGC86391 抗体 MGC88881 抗体