CYP1A1 抗体
(Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008].
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67 results
CYP1A1
适用: 人, 小鼠
WB, IHC (p)
宿主: 兔
Polyclonal
RB16938
unconjugated
1 reference
CYP1A1
适用: 人, 小鼠, 大鼠, 马, Cow, 豚鼠, 兔, 绵羊, 犬, 斑马鱼, 山羊
WB
宿主: 兔
Polyclonal
unconjugated
CYP1A1
适用: 人
WB
宿主: 小鼠
Monoclonal
655CT6-1-2
unconjugated
1 image
5 references
Rockland Original
CYP1A1
适用: 人, 小鼠
WB, IF, IHC (p)
宿主: 兔
Polyclonal
RB16935
unconjugated
Latest Publications for our CYP1A1 抗体
: "Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[a]Pyrene Metabolite Profile and Its Distribution in 3D Skin." in: mBio, Vol. 12, Issue 5, pp. e0122321, (2022) (PubMed).: "Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 8, pp. 1168-1182, (2019) (PubMed).
: "Resveratrol and its methoxy derivatives modulate the expression of estrogen metabolism enzymes in breast epithelial cells by AhR down-regulation." in: Molecular and cellular biochemistry, Vol. 425, Issue 1-2, pp. 169-179, (2017) (PubMed).
: "Benzopyrene, a major polyaromatic hydrocarbon in smoke fume, mobilizes Langerhans cells and polarizes Th2/17 responses in epicutaneous protein sensitization through the aryl hydrocarbon receptor." in: International immunopharmacology, Vol. 36, pp. 111-7, (2016) (PubMed).
: "Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models." in: Archives of toxicology, Vol. 91, Issue 5, pp. 2135-2150, (2016) (PubMed).
: "Inhibition of ?-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation." in: Mutagenesis, Vol. 30, Issue 4, pp. 565-76, (2015) (PubMed).
: "Alterations in ubiquitin ligase Siah-2 and its corepressor N-CoR after P-MAPA immunotherapy and anti-androgen therapy: new therapeutic opportunities for non-muscle invasive bladder cancer." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 4427-43, (2015) (PubMed).
: "Effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine." in: Molecules (Basel, Switzerland), Vol. 19, Issue 9, pp. 14948-60, (2014) (PubMed).
: "Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse." in: Toxicologic pathology, Vol. 40, Issue 8, pp. 1106-16, (2012) (PubMed).
: "Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. ..." in: Human molecular genetics, Vol. 20, Issue 10, pp. 2071-7, (2011) (PubMed).
Aliases for CYP1A1 抗体
cytochrome P450 family 1 subfamily A member 1 (CYP1A1) 抗体cytochrome P450 1A1 (CpipJ_CPIJ010542) 抗体
cytochrome P450, family 1, subfamily a, polypeptide 1 (Cyp1a1) 抗体
cytochrome P450 1A1 (CYP1A1) 抗体
cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) 抗体
cytochrome P450 family 1 subfamily D polypeptide 1 (cyp1d1) 抗体
cytochrome P4501A1 (CYP1A1) 抗体
polycyclic hydrocarbon-inducible cytochrome P450c (LOC100328613) 抗体
cytochrome P450, family 1, subfamily A (cyp1a) 抗体
cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 (CYP1A1) 抗体
cytochrome P450 1A1 (LOC102129994) 抗体
cytochrome P450 family 1 subfamily A member 1 L homeolog (cyp1a1.L) 抗体
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