CYFIP1 抗体
(Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.
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CYFIP1
适用: 人, 小鼠, 大鼠, 斑马鱼, Pig, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴
WB
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our CYFIP1 抗体
: "Cyfip1 is a putative invasion suppressor in epithelial cancers." in: Cell, Vol. 137, Issue 6, pp. 1047-61, (2009) (PubMed).Aliases for CYFIP1 抗体
cytoplasmic FMR1 interacting protein 1 (CYFIP1) 抗体cytoplasmic FMR1 interacting protein 1 (cyfip1) 抗体
cytoplasmic FMR1 interacting protein 1 (Cyfip1) 抗体
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