Cyclin L2 抗体
(Cyclin L2 (CCNL2))
The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].
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Latest Publications for our Cyclin L2 抗体
: "CDK11 Loss Induces Cell Cycle Dysfunction and Death of BRAF and NRAS Melanoma Cells." in: Pharmaceuticals (Basel, Switzerland), Vol. 12, Issue 2, (2019) (PubMed).: "Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance." in: Cell host & microbe, Vol. 17, Issue 1, pp. 98-106, (2015) (PubMed).
: "Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy." in: Breast cancer research : BCR, Vol. 17, pp. 19, (2015) (PubMed).
: "Role of CDK/cyclin complexes in transcription and RNA splicing." in: Cellular signalling, Vol. 17, Issue 9, pp. 1033-51, (2005) (PubMed).
Aliases for Cyclin L2 抗体
cyclin L2 (CCNL2) 抗体cyclin L2 L homeolog (ccnl2.L) 抗体
cyclin L2 (Ccnl2) 抗体
1700010A01Rik 抗体
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2010319M22Rik 抗体
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