This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008].
Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).
Dupays, Mazurais, Rücker-Martin, Calmels, Bernot, Cronier, Malassiné, Gros, Théveniau-Ruissy: "Genomic organization and alternative transcripts of the human Connexin40 gene." in: Gene, Vol. 305, Issue 1, pp. 79-90, (2003) (PubMed).
Cronier, Defamie, Dupays, Théveniau-Ruissy, Goffin, Pointis, Malassiné: "Connexin expression and gap junctional intercellular communication in human first trimester trophoblast." in: Molecular human reproduction, Vol. 8, Issue 11, pp. 1005-13, (2002) (PubMed).
Simon, McWhorter: "Vascular abnormalities in mice lacking the endothelial gap junction proteins connexin37 and connexin40." in: Developmental biology, Vol. 251, Issue 2, pp. 206-20, (2002) (PubMed).
Aliases for Cx40/GJA5 抗体
gap junction protein, alpha 5 (Gja5) 抗体 gap junction protein alpha 5 (GJA5) 抗体 5730555N10Rik 抗体 ATFB11 抗体 Cnx40 抗体 Cx40 抗体 CX40 抗体 Gja-5 抗体