This gene encodes a member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains and one von Willebrand factor A domain. The encoded protein may be involved in membrane trafficking. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008].
Kniazeff, Galvez, Labesse, Pin: "No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 17, pp. 7352-61, (2002) (PubMed).
Ng, Bertrand, Sullivan, Ethier, Wang, Yergey, Belley, Trimble, Bateman, Alder, Smith, McKernan, Metters, ONeill, Lacaille, Hébert: "Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action." in: Molecular pharmacology, Vol. 59, Issue 1, pp. 144-52, (2001) (PubMed).
Margeta-Mitrovic, Jan, Jan: "Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 25, pp. 14649-54, (2001) (PubMed).
Aliases for CPNE7 抗体
copine 7 (CPNE7) 抗体 copine VII (CPNE7) 抗体 copine VII (Cpne7) 抗体 copine 7 (Cpne7) 抗体 AW047065 抗体 CPNE7 抗体