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CPI-17 产品

(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

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The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011].

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Featured CPI-17 Categories

CPI-17 抗体

High quality antibodies with extensive validation data.

CPI-17 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CPI-17 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CPI-17 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (6)
Cat. No. ABIN5518865
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6256551
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN566687
Quantity 100 μg
Datasheet Datasheet

Recommended CPI-17 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380551
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended CPI-17 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315954
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3086388
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3127278
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CPI-17 Products

Xiong, Xia, Tang, Pan, Mei, Xiong: "Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response." in: EBioMedicine, Vol. 9, pp. 45-60, (2016) (PubMed).

Seok, Baek, Kim, Jeong, Lee, Shin, Hwang, Kim: "Isoflavone attenuates vascular contraction through inhibition of the RhoA/Rho-kinase signaling pathway." in: The Journal of pharmacology and experimental therapeutics, Vol. 326, Issue 3, pp. 991-8, (2008) (PubMed).

Lartey, Smith, Pawade, Strachan, Mellor, López Bernal: "Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor." in: Biology of reproduction, Vol. 76, Issue 6, pp. 971-82, (2007) (PubMed).

Hagerty, Weitzel, Chambers, Fortner, Brush, Loiselle, Hosoya, Haystead: "ROCK1 phosphorylates and activates zipper-interacting protein kinase." in: The Journal of biological chemistry, Vol. 282, Issue 7, pp. 4884-93, (2007) (PubMed).

Niiro, Koga, Ikebe: "Agonist-induced changes in the phosphorylation of the myosin- binding subunit of myosin light chain phosphatase and CPI17, two regulatory factors of myosin light chain phosphatase, in smooth muscle." in: The Biochemical journal, Vol. 369, Issue Pt 1, pp. 117-28, (2002) (PubMed).

Hamaguchi, Ito, Feng, Seko, Koyama, Machida, Takase, Amano, Kaibuchi, Hartshorne, Nakano: "Phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by protein kinase N." in: Biochemical and biophysical research communications, Vol. 274, Issue 3, pp. 825-30, (2000) (PubMed).

Synonyms and alternative names related to CPI-17

protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog (ppp1r14a.L), protein phosphatase 1 regulatory inhibitor subunit 14A (ppp1r14a), protein phosphatase 1, regulatory (inhibitor) subunit 14Aa (ppp1r14aa), protein phosphatase 1 regulatory inhibitor subunit 14A (PPP1R14A), protein phosphatase 1, regulatory (inhibitor) subunit 14A (PPP1R14A), protein phosphatase 1, regulatory (inhibitor) subunit 14A (Ppp1r14a), 1110001M11Rik, cpi-17, CPI-17, CPI17, Cpi17, im:7147597, MGC81874, ppp1inl, PPP1INL, ppp1r14a, PPP1R14A, zgc:110700

Protein level used designations for CPI-17

  • protein phosphatase 1, regulatory (inhibitor) subunit 14A
  • protein phosphatase 1 regulatory subunit 14A
  • 17 kDa PKC-potentiated inhibitory protein of PP1
  • 17-KDa protein
  • 17-kDa PKC-potentiated inhibitory protein of PP1
  • PKC-potentiated inhibitory protein of PP1
  • protein kinase C-potentiated inhibitor protein of 17 kDa
  • CPI-17
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