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COX-1 产品

(COX-1)

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This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].

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Recommended COX-1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN3180550
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ICC
Validations
Cat. No. ABIN1575813
Quantity 100 μL
Datasheet Datasheet

Recommended COX-1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122488
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our COX-1 Products

Liu, Tate, Batourina, Truschel, Potter, Adam, Xiang, Picard, Reiley, Schneider, Tamargo, Lu, Chen, He, Kim, Mendelsohn: "Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells." in: Nature communications, Vol. 10, Issue 1, pp. 4589, (2020) (PubMed).

Uram, Filipowicz, Misiorek, Pieńkowska, Markowicz, Wałajtys-Rode, Wołowiec: "Biotinylated PAMAM G3 dendrimer conjugated with celecoxib and/or Fmoc-l-Leucine and its cytotoxicity for normal and cancer human cell lines." in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 124, pp. 1-9, (2019) (PubMed).

Ghosh, Tripathi, Mala, Khurana: "Primary invasive carcinoma of vagina with third degree uterovaginal prolapse: a case report and review of literature." in: Archives of gynecology and obstetrics, (2008) (PubMed).

Asplund, Gry Björklund, Sundquist, Strömberg, Edlund, Ostman, Nilsson, Pontén, Lundeberg: "Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma." in: The British journal of dermatology, Vol. 158, Issue 3, pp. 527-38, (2008) (PubMed).

Ghosh, Novak, Innis: "Cardiac proinflammatory pathways are altered with different dietary n-6 linoleic to n-3 alpha-linolenic acid ratios in normal, fat-fed pigs." in: American journal of physiology. Heart and circulatory physiology, Vol. 293, Issue 5, pp. H2919-27, (2007) (PubMed).

Yokoyama, Tanabe: "Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme." in: Biochemical and biophysical research communications, Vol. 165, Issue 2, pp. 888-94, (1990) (PubMed).

Synonyms and alternative names related to COX-1

cytochrome c oxidase subunit I (COX1), COI
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