This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Dec 2011].
Coghlan, Oberdorf, Sienko, Aiona, Boston, Connelly, Bahney, LaRouche, Almubarak, Coleman, Girkontaite, von der Mark, Lunstrum, Horton: "A degradation fragment of type X collagen is a real-time marker for bone growth velocity." in: Science translational medicine, Vol. 9, Issue 419, (2018) (PubMed).
Aliases for COL8A1 蛋白
collagen type VIII alpha 1 chain (COL8A1) 蛋白 collagen, type VIII, alpha 1 S homeolog (col8a1.S) 蛋白 collagen, type VIII, alpha 1 (Col8a1) 蛋白 collagen type VIII alpha 1 chain (Col8a1) 蛋白 C3orf7 蛋白 Col8a-1 蛋白 COL8A1 蛋白