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COL25A1 产品

(Collagen, Type XXV, alpha 1 (COL25A1))

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This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].

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Featured COL25A1 Categories

COL25A1 抗体

High quality antibodies with extensive validation data.

COL25A1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended COL25A1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN529727
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN949736
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6257062
Quantity 100 μL
Datasheet Datasheet

Recommended COL25A1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349959
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349958
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
Cat. No. ABIN3128069
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our COL25A1 Products

Spivey, Banyard, Solis, Wistuba, Barletta, Gandhi, Feldman, Rodig, Chirieac, Zetter: "Collagen XXIII: a potential biomarker for the detection of primary and recurrent non-small cell lung cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1362-72, (2010) (PubMed).

Synonyms and alternative names related to COL25A1

collagen type XXV alpha 1 chain (COL25A1), collagen, type XXV, alpha 1 (COL25A1), collagen type XXV alpha 1 chain (col25a1), collagen, type XXV, alpha 1 (Col25a1), collagen type XXV alpha 1 chain (Col25a1), 2700062B08Rik, AMY, CLAC, CLAC-P, CLACP, COL25A1

Protein level used designations for COL25A1

  • collagen, type XXV, alpha 1
  • collagen, type XXV, alpha 1-like
  • collagen alpha-1(XXV) chain-like
  • alzheimer disease amyloid-associated protein
  • collagen alpha-1(XXV) chain
  • collagen-like Alzheimer amyloid plaque component
  • collagenous Alzheimer amyloid plaque component
  • procollagen, type XXV, alpha 1
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