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CNR2 产品

(Cannabinoid Receptor 2 (CNR2))
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008].

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Featured CNR2 Categories

CNR2 抗体

High quality antibodies with extensive validation data.

CNR2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CNR2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CNR2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (2)
  • (6)
Cat. No. ABIN654631
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (4)
Cat. No. ABIN680168
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (4)
Cat. No. ABIN514506
Quantity 100 μg
Datasheet Datasheet

Recommended CNR2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954322
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965381
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674677
Quantity 96 tests
Datasheet Datasheet

Recommended CNR2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964233
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349885
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349883
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CNR2 Products

Braun, Khan, Khan, Kumar, Ward, Achyut, Arbab, Hess, Hoda, Baban, Dhandapani, Vaibhav: "Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization." in: Brain, behavior, and immunity, Vol. 68, pp. 224-237, (2017) (PubMed).

Kamikubo, Kai, Tsuji-Naito, Akagawa: "β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes." in: Molecular nutrition & food research, Vol. 60, Issue 10, pp. 2228-2242, (2017) (PubMed).

Hu, Zhou, Wang, Lu, Yin: "N-stearoyl-l-Tyrosine inhibits the cell senescence and apoptosis induced by H2O2 in HEK293/Tau cells via the CB2 receptor." in: Chemico-biological interactions, Vol. 272, pp. 135-144, (2017) (PubMed).

Wang, Zheng, Kulkarni, Wang, Garg, Prather, Hauer-Jensen: "Palmitoylethanolamide regulates development of intestinal radiation injury in a mast cell-dependent manner." in: Digestive diseases and sciences, Vol. 59, Issue 11, pp. 2693-703, (2015) (PubMed).

Fügedi, Molnár, Rigó, Schönléber, Kovalszky, Molvarec: "Increased placental expression of cannabinoid receptor 1 in preeclampsia: an observational study." in: BMC pregnancy and childbirth, Vol. 14, pp. 395, (2015) (PubMed).

Wilhelmsen, Khakpour, Tran, Sheehan, Schumacher, Xu, Hellman: "The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13079-100, (2014) (PubMed).

Brocato, Zoerner, Janjetovic, Skobowiat, Gupta, Moore, Slominski, Zhang, Schenone, Phinehas, Ferry, Dick, Hubbard, Mari, Schlabritz-Loutsevitch: "Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity." in: Placenta, Vol. 34, Issue 11, pp. 983-9, (2013) (PubMed).

Patsenker, Stoll, Millonig, Agaimy, Wissniowski, Schneider, Mueller, Brenneisen, Seitz, Ocker, Stickel: "Cannabinoid receptor type I modulates alcohol-induced liver fibrosis." in: Molecular medicine (Cambridge, Mass.), Vol. 17, Issue 11-12, pp. 1285-94, (2012) (PubMed).

Van Sickle, Duncan, Kingsley, Mouihate, Urbani, Mackie, Stella, Makriyannis, Piomelli, Davison, Marnett, Di Marzo, Pittman, Patel, Sharkey: "Identification and functional characterization of brainstem cannabinoid CB2 receptors." in: Science (New York, N.Y.), Vol. 310, Issue 5746, pp. 329-32, (2005) (PubMed).

Synonyms and alternative names related to CNR2

cannabinoid receptor 2 (CNR2), cannabinoid receptor 2 (cnr2), cannabinoid receptor 2 (Cnr2), cannabinoid receptor 2 (macrophage) (Cnr2), CB-2, CB2, CB2-R, cb2a, cb2b, CB2C, CNR2, CNR2C, CX5

Protein level used designations for CNR2

  • cannabinoid receptor 2 (macrophage)
  • cannabinoid receptor 2
  • CB2R
  • cannabinoid receptor 2 type A
  • cannabinoid receptor-like cb2-zf
  • testis-dominant CNR2 isoform CB2
  • CB2 receptor
  • peripheral cannabinoid receptor
  • rCB2
  • cannabinoid receptor 2 (spleen)
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