(Connector Enhancer of Kinase Suppressor of Ras 2 (CNKSR2))
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
custom-made
CNKSR2
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, ELISA, WB
custom-made
CNKSR2
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, ELISA, WB
David, Surendran, Thulaseedharan, Nair: "Regulation of CNKSR2 protein stability by the HECT E3 ubiquitin ligase Smurf2, and its role in breast cancer progression." in: BMC cancer, Vol. 18, Issue 1, pp. 284, (2018) (PubMed).
Aliases for CNKSR2 蛋白
connector enhancer of kinase suppressor of Ras 2 (CNKSR2) 蛋白 connector enhancer of kinase suppressor of Ras 2 (Cnksr2) 蛋白 C030004A01 蛋白 CNK2 蛋白 Cnk2 蛋白 KSR2 蛋白 Ksr2 蛋白 MAGUIN 蛋白 mKIAA0902 蛋白