Clvs1/2 抗体 (C-Term)
This anti-Clvs1/2 antibody is a 兔 多克隆 antibody detecting Clvs1/2 in IF 和 WB. Suitable for 人, 小鼠 和 大鼠.
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Quick Overview for Clvs1/2 抗体 (C-Term) (ABIN784598)
抗原
Clvs1/2
(Clavesin 1/2 (Clvs1/2))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
应用范围
Immunofluorescence (IF), Western Blotting (WB)
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抗原表位
- C-Term
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特异性
- Specific for the ~35 kDa Clavesin 1/2 protein doublet in Western blots of Rat brain lysate. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are Clavesin 1 and 2, respectively.
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交叉反应 （详细）
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Species reactivity (expected):Human and Mouse.
Species reactivity (tested):Rat. -
纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic peptide KLH-conjugated corresponding to amino acid residues from the C-terminal region of Rat Clavesin-1. Genename: CLVS1/2
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- Clvs1/2 (Clavesin 1/2 (Clvs1/2))
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背景
- Clavesin (clathrin vesicle associated Sec14 protein) is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects (Katoh et al., 2009). Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state (Zhao et al., 2008).Synonyms: C6orf212, C6orf213, CLVS1, CLVS2, CRALBPL, Cellular retinaldehyde-binding protein-like, RLBP1L1, RLBP1L2, Retinaldehyde-binding protein 1-like 1/2
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基因ID
- 366311
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NCBI登录号
- NP_001102439
抗原
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