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PRMT5 蛋白

9 results:

Protein Arginine Methyltransferase 5 (PRMT5) (AA 1-637) protein (His tag) Protein

Crystallography grade PRMT5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
产品编号 ABIN3089077
$10,832.86
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping 发货至: 美国
60个工作日

Protein Arginine Methyltransferase 5 (PRMT5) (AA 2-637) protein (His tag) Protein

Crystallography grade PRMT5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
产品编号 ABIN3089078
$10,832.86
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping 发货至: 美国
60个工作日

Protein Arginine Methyltransferase 5 (PRMT5) (AA 2-637) protein (His tag) Protein

Crystallography grade PRMT5 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
产品编号 ABIN3136486
$10,832.86
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping 发货至: 美国
60个工作日

Protein Arginine Methyltransferase 5 (PRMT5) protein (DYKDDDDK Tag) Protein

PRMT5 宿主: 人 宿主: Baculovirus Recombinant EAA, ScA
产品编号 ABIN2669658
$513.33
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping 发货至: 美国
1至2个工作日

Protein Arginine Methyltransferase 5 (PRMT5) (AA 1-637) protein (GST tag) Protein

PRMT5 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Pubmed 1
产品编号 ABIN1316333
$574.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping 发货至: 美国
11至12个工作日

Protein Arginine Methyltransferase 5 (PRMT5) (AA 2-637) protein (DYKDDDDK Tag,His tag) Protein

PRMT5 宿主: 人 宿主: 人细胞 Recombinant > 85 % as determined by SDS-PAGE SDS
产品编号 ABIN2003914
$506.74
加上运输费 $45.00
50 μg (More quantities available)
local_shipping 发货至: 美国
11至13个工作日

Protein Arginine Methyltransferase 5 (PRMT5) (AA 531-637) protein (GST tag) Protein

PRMT5 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
产品编号 ABIN1316335
$574.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping 发货至: 美国
11至12个工作日

Protein Arginine Methyltransferase 5 (PRMT5) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

PRMT5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
产品编号 ABIN2729673
$1,019.70
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping 发货至: 美国
11个工作日

Protein Arginine Methyltransferase 5 (PRMT5) protein (GST tag) Protein

PRMT5 宿主: 人 宿主: Baculovirus infected Insect Cells, Insect cells (Sf9) WB
产品编号 ABIN6700420
$562.00
Plus shipping costs $45.00 and $24.00 dry ice
50 μg
local_shipping 发货至: 美国
1至2个工作日
  • 类型 Protein
    • Protein
  • 抗原 Protein Arginine Methyltransferase 5 (PRMT5)
    • Protein Arginine Methyltransferase 5 (PRMT5)
    • Hemagglutinin (HA)
    • Hemoglobin beta (HBB)
    • Ribosome Binding Factor A (RBFA)
    • Triosephosphate Isomerase 1 (TPI1)
    • S-Adenosyl-Methionine Synthase (METK)
    • Hemoglobin, alpha 1 (HBA1)
    • SARS-CoV-2 Spike
    • Myoglobin (MB)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • Thymidylate Kinase (Tmk)
    • Lipoyl synthase (lipA)
    • Growth Hormone 1 (GH1)
    • Interferon gamma (IFNG)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Aspartate Carbamoyltransferase (PYRB)
    • Uracil-DNA Glycosylase (UNG)
    • Malate Dehydrogenase (MDH)
    • Phosphoglucosamine Mutase (GLMM)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • phosphatidylserine Decarboxylase (PISD)
    • Cysteinyl-tRNA Synthetase 2, Mitochondrial (Putative) (CARS2)
    • tRNA Methyltransferase 5 (TRMT5)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Interleukin 6 (IL6)
    • Interleukin 2 (IL2)
    • Cytochrome C, Somatic (CYCS)
    • Interleukin 4 (IL4)
    • Epidermal Growth Factor Receptor (EGFR)
    • CD40 Ligand (CD40LG)
    • Gp120
    • Porphobilinogen Deaminase (HEMC)
    • Plasminogen Activator Inhibitor 1 (SERPINE1)
    • Superoxide Dismutase 1, Soluble (SOD1)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • 1-(5-Phosphoribosyl)-5-[(5-Phosphoribosylamino)methylideneamino] Imidazole-4-Carboxamide Isomerase (APG10)
    • Interleukin 10 (IL10)
    • Interleukin 8 (IL8)
    • Interleukin 1, beta (IL1B)
    • Prolactin (PRL)
    • Adenosylhomocysteinase (AHCY)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Ferrochelatase, HEMH (HEMH)
    • Thymidylate Synthase (THYA)
    • Programmed Cell Death 1 (PDCD1)
    • SARS-CoV-2 Spike S1
    • Thymidine Kinase 1, Soluble (TK1)
    • Uracil Phosphoribosyltransferase (UPP)
    • beta-2-Microglobulin (B2M)
    • Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
    • Insulin-Like Growth Factor 1 (IGF1)
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Enzyme Activity Assay (EAA)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Screening Assay (ScA)
    • Standard (STD)
  • 适用
    • 小鼠
  • 论文引用
  • 图像
  • 抗体来源
    • Insect Cells
    • 小麦胚
    • Baculovirus
    • Baculovirus infected Insect Cells
    • HEK-293 Cells
    • 人细胞
    • Insect cells (Sf9)
  • 抗原表位
    • AA 2-637
    • AA 1-637
    • AA 531-637
    • Transcript Variant 1
  • 标记
    • 非结合性
    • GST tag
    • His tag
    • DYKDDDDK Tag
    • DYKDDDDK Tag,His tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Crystallography grade

蛋白简介PRMT5

蛋白简介

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3)\; such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10. Attenuates EGF signaling through the MAPK1/MAPK3 pathway acting at 2 levels. First, monomethylates EGFR\; this enhances EGFR 'Tyr-1197' phosphorylation and PTPN6 recruitment, eventually leading to reduced SOS1 phosphorylation. Second, methylates RAF1 and probably BRAF, hence destabilizing these 2 signaling proteins and reducing their catalytic activity (By similarity). Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation (By similarity). Methylates HOXA9 (By similarity).

Alternative names and synonyms associated with PRMT5

  • protein arginine methyltransferase 5 (PRMT5) 抗体
  • protein arginine N-methyltransferase 5 (Prmt5) 抗体
  • protein arginine methyltransferase 5 (Prmt5) 抗体
  • protein arginine methyltransferase 5 (prmt5) 抗体
  • protein arginine methyltransferase 5 L homeolog (prmt5.L) 抗体
  • putative arginine N-methyltransferase, type II (PRMT5) 抗体
  • Skb1 family protein (prmt5) 抗体
  • protein arginine N-methyltransferase 5 (LOC100115766) 抗体
  • Protein arginine N-methyltransferase 5 (prmt-5) 抗体
  • DDBDRAFT_0187422 抗体
  • DDBDRAFT_0235403 抗体
  • DDB_0187422 抗体
  • DDB_0235403 抗体
  • hrmt1l5 抗体
  • hsl7 抗体
  • ibp72 抗体
  • jbp1 抗体
  • NV18830 抗体
  • si:zc14a17.2 抗体
  • skb1 抗体
  • skb1hs 抗体
  • wu:fb95f10 抗体
  • zgc:110669 抗体

Protein level used designations for PRMT5

72 kDa ICln-binding protein , HMT1 hnRNP methyltransferase-like 5 , SKB1 homolog , histone-arginine N-methyltransferase PRMT5 , jak-binding protein 1 , protein arginine N-methyltransferase 5 , shk1 kinase-binding protein 1 homolog , protein arginine methyltransferase 5 , Jak-binding protein 1 , putative arginine N-methyltransferase, type II , protein arginine methyltransferase , protein arginine N-methyltransferase 5-like

GENE ID SPECIES
10419 Homo sapiens
100583805 Nomascus leucogenys
27374 Mus musculus
364382 Rattus norvegicus
368664 Danio rerio
515594 Bos taurus
100173581 Pongo abelii
452789 Pan troglodytes
480242 Canis lupus familiaris
495515 Xenopus laevis
712718 Macaca mulatta
5068851 Leishmania infantum JPCM5
8626071 Dictyostelium discoideum AX4
100024287 Monodelphis domestica
100052729 Equus caballus
100115766 Nasonia vitripennis
100144380 Oryzias latipes
100145788 Xenopus (Silurana) tropicalis
100294711 Sus scrofa
100357415 Oryctolagus cuniculus
100473723 Ailuropoda melanoleuca
100555438 Anolis carolinensis
175717 Caenorhabditis elegans
100731218 Cavia porcellus

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