蛋白简介

Component of the gypsy chromatin insulator complex which is required for the function of the gypsy chromatin insulator and other endogenous chromatin insulators. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties\; they can block the communication between an enhancer and a promoter when placed between them and can also buffer transgenes from position effect variegation (PEV). Insulators are proposed to structure the chromatin fiber into independent domains of differing transcriptional potential by promoting the formation of distinct chromatin loops. This chromatin looping may involve the formation of insulator bodies, where homotypic interactions between individual subunits of the insulator complex could promote the clustering of widely spaced insulators at the nuclear periphery. Within the gypsy insulator complex, this protein may control the nature of the repressive exerts a bidirectional silencing effect, whereas in the presence of mod(mdg4), the silencing effect is unidirectional. Isoform H is specifically required to maintain the pairing of achiasmate homologs in male meiosis I which is mediated by the rDNA repeats on the achiasmate X-Y bivalents. Isoform H also plays a role in apoptotic regulatory pathways.

Alternative names and synonyms associated with Modifier of Mdg4 (MOD(MDG4))

• modifier of mdg4 (mod(mdg4)) 抗体

• BcDNA:GH07769 抗体
• BcDNA:SD03001 抗体
• bpd 抗体
• CG7836 抗体
• CG7859 抗体
• 显示所有的同义词和别名
• CG8076 抗体
• CG15500 抗体
• CG15501 抗体
• CG15802 抗体
• CG18151 抗体
• CG32491 抗体
• Dmel\\CG32491 抗体
• doom 抗体
• E(var)3-93D 抗体
• E(var)93D 抗体
• E(var)129 抗体
• E-(var)3-93D 抗体
• E-var(3)1 抗体
• E-var(3)3 抗体
• l(3)03852 抗体
• l(3)j2B7 抗体
• l(3)L3101 抗体
• mdg4 抗体
• mnm 抗体
• mnn 抗体
• mod 抗体
• mod(gypsy) 抗体
• Mod(mdg)4 抗体
• mod(mdg-4) 抗体
• mod(mdg4 抗体
• Mod(mdg4) 抗体
• mod(mdg4)-67.2 抗体
• Mod(mdg4)2.2 抗体
• MOD(MDG4)56.3 抗体
• mod(mdg4)67.2 抗体
• mod2.2 抗体
• mod[mdg4] 抗体
• pf-2 抗体

Protein level used designations for MOD(MDG4)

CG32491-PA , CG32491-PAA , CG32491-PAB , CG32491-PAC , CG32491-PAD , CG32491-PAE , CG32491-PB , CG32491-PC , CG32491-PD , CG32491-PE , CG32491-PF , CG32491-PG , CG32491-PH , CG32491-PI , CG32491-PJ , CG32491-PK , CG32491-PL , CG32491-PM , CG32491-PN , CG32491-PO , CG32491-PP , CG32491-PQ , CG32491-PR , CG32491-PS , CG32491-PT , CG32491-PU , CG32491-PV , CG32491-PW , CG32491-PX , CG32491-PY , CG32491-PZ , Modifier67.2 , branch point disrupted , enhancer of variegation 93D , mod(mdg4)-PA , mod(mdg4)-PAA , mod(mdg4)-PAB , mod(mdg4)-PAC , mod(mdg4)-PAD , mod(mdg4)-PAE , mod(mdg4)-PB , mod(mdg4)-PC , mod(mdg4)-PD , mod(mdg4)-PE , mod(mdg4)-PF , mod(mdg4)-PG , mod(mdg4)-PH , mod(mdg4)-PI , mod(mdg4)-PJ , mod(mdg4)-PK , mod(mdg4)-PL , mod(mdg4)-PM , mod(mdg4)-PN , mod(mdg4)-PO , mod(mdg4)-PP , mod(mdg4)-PQ , mod(mdg4)-PR , mod(mdg4)-PS , mod(mdg4)-PT , mod(mdg4)-PU , mod(mdg4)-PV , mod(mdg4)-PW , mod(mdg4)-PX , mod(mdg4)-PY , mod(mdg4)-PZ , modifier mdg4 , modifier of mdg4 67.2 , modifier of mdg4 in meiosis , modifier of midget4