anti-FOXP3 (FOXP3) 抗体产品概述

Full name:: anti-Forkhead Box P3 抗体 (FOXP3)

在www.antibodies-online.cn可供564 Forkhead Box P3 (FOXP3) 抗体的37不同的供货商。再加上，我们可以发FOXP3 试剂盒 (61) 和 FOXP3 蛋白 (18)和数多这个蛋白质的别的产品。总共667 FOXP3产品已列进来了。

别名:: AIID, DIETER, FOXP3, IPEX, JM2, PIDX, RGD1562112, scurfin, sf, XPID

列出全部抗体	基因	基因ID	UniProt
	FOXP3	50943	Q9BZS1
	FOXP3	20371	Q99JB6
	FOXP3	317382
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Activated T Cell Proliferation

引用最多的anti-FOXP3 抗体

Human Polyclonal FOXP3 Primary Antibody for ChIP, ICC - ABIN153182 : Andersson, Boasso, Nilsson, Zhang, Shire, Lindback, Shearer, Chougnet: The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
Show all 15 Pubmed References
Mouse (Murine) Monoclonal FOXP3 Primary Antibody for ICC, IHC - ABIN1169339 : Lan, Wang, Raimondi, Wu, Colvin, de Creus, Thomson: "Alternatively activated" dendritic cells preferentially secrete IL-10, expand Foxp3+CD4+ T cells, and induce long-term organ allograft survival in combination with CTLA4-Ig. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
Show all 7 Pubmed References
Human Polyclonal FOXP3 Primary Antibody for ICC, FACS - ABIN188539 : Grant, Jung, Johnson, Kostakoglu, Hsi, Byrd, Jones, Leonard, Martin, Cheson: A phase 2 trial of extended induction epratuzumab and rituximab for previously untreated follicular lymphoma: CALGB 50701. in Cancer 2013 (PubMed)
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Human Polyclonal FOXP3 Primary Antibody for IHC (p) - ABIN3042405 : Li, Ren, Wang, Gu, Hu, Ren, Hong, Wu, Liu, Li: T2 enhances in situ level of Foxp3+ regulatory cells and modulates inflammatory cytokines in Crohn's disease. in International immunopharmacology 2014 (PubMed)
Show all 6 Pubmed References
Human Polyclonal FOXP3 Primary Antibody for WB - ABIN3043158 : Fu, Li, Yang, Gai, Jia, Lei, Li: FOXP3 and TLR4 protein expression are correlated in non-small cell lung cancer: implications for tumor progression and escape. in Acta histochemica 2013 (PubMed)
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Human Polyclonal FOXP3 Primary Antibody for ICC, IF - ABIN153185 : Ostroukhova, Qi, Oriss, Dixon-McCarthy, Ray, Ray: Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta. in The Journal of clinical investigation 2006 (PubMed)
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Baboon Monoclonal FOXP3 Primary Antibody for ICS, IHC - ABIN2689510 : Brunkow, Jeffery, Hjerrild, Paeper, Clark, Yasayko, Wilkinson, Galas, Ziegler, Ramsdell: Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. in Nature genetics 2001 (PubMed)
Show all 3 Pubmed References
Polyclonal FOXP3 Primary Antibody for WB - ABIN540720 : Lim, Hillsamer, Banham, Kim: Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
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Human Monoclonal FOXP3 Primary Antibody for ELISA, WB - ABIN969156 : Yuan, Chen, Li, Dong, Xue, Wang, Zhang, Wang, Zhang, Ge, Shen, Xu: Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner. in Clinical immunology (Orlando, Fla.) 2010 (PubMed)
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Human Polyclonal FOXP3 Primary Antibody for IHC (fro), IHC (p) - ABIN153186 : Wilcox, Feldman, Wada, Yang, Comfere, Dong, Kwon, Novak, Markovic, Pittelkow, Witzig, Ansell: B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders. in Blood 2009 (PubMed)
Show all 2 Pubmed References

更多抗FOXP3的相互作用对抗体

Zebrafish Forkhead Box P3 (FOXP3) interaction partners

analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish
correlation between the expression of t-bet, stat6 (显示 STAT6 抗体) and foxp3 with other genes involved in Th and T(reg (显示 KCNH2 抗体)) responses

Atlantic Salmon (Salmo salar) Forkhead Box P3 (FOXP3) interaction partners

cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals

Human Forkhead Box P3 (FOXP3) interaction partners

It was concluded that the abnormal expression of endometrial E2A (显示 TCF3 抗体) existed in mid-secretory endometrium of women with recurrent miscarriage, and there was a positive correlation between E2A (显示 TCF3 抗体) and FOXP3, and E2A (显示 TCF3 抗体) and CTLA-4 (显示 CTLA4 抗体), suggesting the possible regulatory role of E2A (显示 TCF3 抗体) in endometrium receptivity.
Lymphocytic enteritis associated to celiac disease shows an increase of FOXP3 expression and lymphocytes T-gammadelta that is not detected in other etiologies of enteritis.
Downregulated expression of FOXP3 by siRNA transfection significantly inhibited cell proliferation and enhanced chemosensitivity to cisplatin in A549 lung adenocarcinoma cells.
Foxp3 is associated with lymphangiogenesis of cervical cancer.
Polymorphic marker -3279 C>A of the FOXP3 gene was not associated with the risk of Pulmonary Sarcoidosis patients of Russian ethnicity.
Data show that forkhead box P3 protein (显示 SLC10A3 抗体) (FOXP3) protein not only binds with DNA sequences containing one FKH (显示 FOXA1 抗体) consensus sequence, but also binds with DNA sequences with two direct repeats of consensus sequences separated by three-nucleotides (DRE3).
Study identifies CCR8 (显示 CCR8 抗体)+ regulatory T cells (Treg cells) as drivers of immunosuppression and provides compelling evidence of a self-feeding mechanism by which, at an autoimmune site, CCL1 (显示 CCL1 抗体) produced by FOXp3+ Treg cells upregulates the expression of its own receptor, CCR8 (显示 CCR8 抗体), on these cells, and potentiates their in vivo proliferation and suppressive activities as driver Treg cells.
our findings suggest that FOXP3 suppresses tumor progression in hepatocellular carcinoma (HCC (显示 FAM126A 抗体)) via TGF-b/Smad2 (显示 SMAD2 抗体)/3 signaling pathway, highlighting the role of FOXP3 as a prognostic factor and novel target for an optimal therapy against this fatal malignancy
Studied lymphocyte phenotype in resected lymph nodes of patients with lung cancer by analyzing levels of Foxp3 and CD8 (显示 CD8A 抗体) by immunohistochemical staining.
We conclude that Foxp3 promoter polymorphisms are associated with susceptibility to endometrial cancer in Chinese Han women.

Mouse (Murine) Forkhead Box P3 (FOXP3) interaction partners

Unexpectedly, although dispensable for FOXP3 expression and for the homeostasis and suppressive function of thymus-derived Treg cells, CREB (显示 CREB1 抗体) negatively regulates the survival of TGF-beta (显示 TGFB1 抗体)-induced Treg cells, and deletion of CREB (显示 CREB1 抗体) resulted in increased FOXP3+ Treg cells in the intestine and protection in a colitis model
This study reports on systematic alanine-scan mutagenesis of FoxP3, assessing mutational impacts on DNA binding and transcriptional activation or repression.
Foxp3 is essential for beneficial outcome of the microglial response and depends upon signalling by the immunoglobulin CD200 (显示 CD200 抗体) through its receptor (CD200R (显示 CD200R1 抗体))
Tbet is a critical modulator of FoxP3 expression in autoimmune graft-versus-host disease
Generation of RORgammat(+) antigen-specific T17 regulatory cells from Foxp3(+) precursors in autoimmunity has been described.
KLRG1 (显示 KLRG1 抗体) expression identifies short-lived Foxp3(+) Treg effector cells with functional plasticity in islets of NOD mice.
Novel regulatory T-cells that are induced by B cells and do not express Foxp3 and IL-10 (显示 IL10 抗体) alleviate intestinal inflammation in vivo.
the findings suggested that excreted-secreted antigens restricted Foxp3 expression by inhibiting TGFssRII/Smad2 (显示 SMAD2 抗体)/Smad3 (显示 SMAD3 抗体)/Smad4 (显示 SMAD4 抗体) signalling, ultimately resulting in abortion.
Data (including data from studies using transgenic mice) suggest that a single oral dose of vitamin A (1) amplifies tolerogenic activity of dendritic cells migrating to lymphoid tissue and (2) up-regulates expression of Foxp3 and Cd44 (显示 CD44 抗体) in co-cultures of dendritic cells and CD4 (显示 CD4 抗体)+ lymphocytes. (Foxp3 = forkhead box P3; Cd44 (显示 CD44 抗体) = homing receptor)
Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity.

Pig (Porcine) Forkhead Box P3 (FOXP3) interaction partners

sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids
In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection

Cow (Bovine) Forkhead Box P3 (FOXP3) interaction partners

GWAS identified a maternal variant in the upstream region of FOXP3 that was associated with infertility in repeat-breeding Japanese Black cattle that failed to conceive using embryo transfer. The variant affected the level of FOXP3 mRNA expression.
Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (显示 CTLA4 抗体).
The expression of Foxp3 in CD4 (显示 CD4 抗体)(+) T cells from persistent lymphocytotic cattle was significantly increased.
There is a positive correlation between the intensity of CD25 (显示 IL2RA 抗体) expression and the expression of the transcription Foxp3 factor in bovine CD8 (显示 CD8A 抗体)(+) cells.
identification of Foxp3 expression in Treg cells
These findings revealed that despite the existence of a distinct bovine CD4 (显示 CD4 抗体)(+)CD25 (显示 IL2RA 抗体)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population

Horse (Equine) Forkhead Box P3 (FOXP3) interaction partners

The correlation of TH17-related TLR4 (显示 TLR4 抗体) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.
Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.
results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response

FOXP3 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with FOXP3

forkhead box P3 (FOXP3) 抗体
forkhead box P3a (foxp3a) 抗体
forkhead box P3 (foxp3) 抗体
forkhead box P3 L homeolog (foxp3.L) 抗体
forkhead box P3 (Foxp3) 抗体

AIID 抗体
DIETER 抗体
FOXP3 抗体
IPEX 抗体
JM2 抗体
PIDX 抗体
RGD1562112 抗体
scurfin 抗体
sf 抗体
XPID 抗体

Protein level used designations for anti-Forkhead Box P3 (FOXP3) 抗体

forkhead box protein P3 , regulatory protein Foxp3 , scurfin , forkhead box P3 , forkhead box protein P3-like , transcription factor foxp3 , FOXP3delta7 , immune dysregulation, polyendocrinopathy, enteropathy, X-linked , immunodeficiency, polyendocrinopathy, enteropathy, X-linked , scurfy , forkhead/winged helix transcription factor 3

GENE ID	SPECIES
574303	Macaca mulatta
571165	Danio rerio
740909	Pan troglodytes
100037405	Felis catus
100348270	Oryctolagus cuniculus
100467988	Ailuropoda melanoleuca
100526661	Salmo salar
100158268	Xenopus laevis
50943	Homo sapiens
491876	Canis lupus familiaris
20371	Mus musculus
444998	Sus scrofa
506053	Bos taurus
317382	Rattus norvegicus
100052226	Equus caballus
100735602	Cavia porcellus
100240742	Ovis aries

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