CHD4 抗体
(Chromodomain Helicase DNA Binding Protein 4 (CHD4))
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. [provided by RefSeq, Jul 2008].
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Latest Publications for our CHD4 抗体
: "Dermatomyositis autoantigen CHD4 forms immune stimulatory complexes with endogenous DNA." in: Experimental dermatology, (2023) (PubMed).: "Distinct Requirements of CHD4 during B Cell Development and Antibody Response." in: Cell reports, Vol. 27, Issue 5, pp. 1472-1486.e5, (2019) (PubMed).
: "CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity." in: The Journal of clinical investigation, Vol. 126, Issue 6, pp. 2254-66, (2016) (PubMed).
: "Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex." in: The Journal of biological chemistry, Vol. 289, Issue 42, pp. 28956-70, (2014) (PubMed).
: "Runx1 regulation of Pu.1 corepressor/coactivator exchange identifies specific molecular targets for leukemia differentiation therapy." in: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 14881-95, (2014) (PubMed).
: "The NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis." in: PLoS genetics, Vol. 9, Issue 12, pp. e1004031, (2013) (PubMed).
: "The chromatin-remodeling enzymes BRG1 and CHD4 antagonistically regulate vascular Wnt signaling." in: Molecular and cellular biology, Vol. 32, Issue 7, pp. 1312-20, (2012) (PubMed).
: "Sin3a is essential for the genome integrity and viability of pluripotent cells." in: Developmental biology, Vol. 363, Issue 1, pp. 62-73, (2012) (PubMed).
: "Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 450-9, (2011) (PubMed).
: "Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development." in: Biology of reproduction, Vol. 83, Issue 6, pp. 1027-35, (2010) (PubMed).
Aliases for CHD4 抗体
chromodomain helicase DNA binding protein 4 (CHD4) 抗体chromodomain helicase DNA binding protein 4a (chd4a) 抗体
chromodomain helicase DNA binding protein 4b (chd4b) 抗体
chromodomain helicase DNA binding protein 4 (chd4) 抗体
chromodomain helicase DNA binding protein 4 (Chd4) 抗体
chromodomain helicase DNA binding protein 4 L homeolog (chd4.L) 抗体
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