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CHAF1B 产品

(Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))

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Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008].

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Featured CHAF1B Categories

CHAF1B 抗体

High quality antibodies with extensive validation data.

CHAF1B ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CHAF1B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CHAF1B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet

Application WB
Validations
  • (1)
  • (7)
Cat. No. ABIN2782376
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7011014
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN950155
Quantity 50 μg
Datasheet Datasheet

Recommended CHAF1B ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954773
Quantity 96 tests
Datasheet Datasheet

Recommended CHAF1B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349274
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349276
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
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  • (1)
Cat. No. ABIN3090549
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CHAF1B Products

Zaidan, Walker, Brown, Schaffer, Scalf, Shortreed, Iyer, Smith, Sridharan: "Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance." in: Stem cell reports, Vol. 10, Issue 2, pp. 627-641, (2019) (PubMed).

Cohen, Corpet, Roubille, Maroui, Poccardi, Rousseau, Kleijwegt, Binda, Texier, Sawtell, Labetoulle, Lomonte: "Promyelocytic leukemia (PML) nuclear bodies (NBs) induce latent/quiescent HSV-1 genomes chromatinization through a PML NB/Histone H3.3/H3.3 Chaperone Axis." in: PLoS pathogens, Vol. 14, Issue 9, pp. e1007313, (2019) (PubMed).

Volk, Liang, Suraneni, Li, Zhao, Bulic, Marshall, Pulakanti, Malinge, Taub, Ge, Rao, Bartom, Shilatifard, Crispino: "A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis." in: Cancer cell, Vol. 34, Issue 5, pp. 707-723.e7, (2018) (PubMed).

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Elsaesser, Allis: "HIRA and Daxx constitute two independent histone H3.3-containing predeposition complexes." in: Cold Spring Harbor symposia on quantitative biology, Vol. 75, pp. 27-34, (2011) (PubMed).

Galvani, Courbeyrette, Agez, Ochsenbein, Mann, Thuret: "In vivo study of the nucleosome assembly functions of ASF1 histone chaperones in human cells." in: Molecular and cellular biology, Vol. 28, Issue 11, pp. 3672-85, (2008) (PubMed).

Green, Almouzni: "Local action of the chromatin assembly factor CAF-1 at sites of nucleotide excision repair in vivo." in: The EMBO journal, Vol. 22, Issue 19, pp. 5163-74, (2003) (PubMed).

Shibahara, Stillman: "Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin." in: Cell, Vol. 96, Issue 4, pp. 575-85, (1999) (PubMed).

Kaufman, Kobayashi, Kessler, Stillman: "The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication." in: Cell, Vol. 81, Issue 7, pp. 1105-14, (1995) (PubMed).

Smith, Stillman: "Immunological characterization of chromatin assembly factor I, a human cell factor required for chromatin assembly during DNA replication in vitro." in: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 12041-7, (1991) (PubMed).

Synonyms and alternative names related to CHAF1B

chromatin assembly factor 1 subunit B (CHAF1B), chromatin assembly factor 1 subunit B (chaf1b), chromatin assembly factor 1, subunit B (chaf1b), chromatin assembly factor 1, subunit B (p60) (Chaf1b), chromatin assembly factor 1 subunit B L homeolog (chaf1b.L), chromatin assembly factor 1 subunit B (Chaf1b), 2600017H24Rik, C76145, CAF-1, caf-1, CAF-1P60, CAF-IP60, CAF-I p60, CAF-Ip60, CAF1, CAF1A, CAF1P60, CHAF1B, MPHOSPH7, MPP7, wu:fd07c09, wu:fe36g06, wu:fv38g09, zgc:56096

Protein level used designations for CHAF1B

  • chromatin assembly factor 1, subunit B (p60)
  • chromatin assembly factor 1 subunit B
  • chromatin assembly factor 1 subunit B-like
  • fe36g06
  • CAF-1 subunit B
  • CAF-I 60 kDa subunit
  • CAF-I p60
  • M-phase phosphoprotein 7
  • chromatin assembly factor I p60 subunit
  • human chromatin assembly factor-I p60 subunit
  • chromatin assembly factor-1 p60 subunit
  • CAF-Ip60
  • chromatin assembly factor-1p60
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