CFHR4 抗体
(Complement Factor H-Related 4 (CFHR4))
This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene. [provided by RefSeq, Jan 2011].
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Latest Publications for our CFHR4 抗体
: "Factor H-related protein 4 activates complement by serving as a platform for the assembly of alternative pathway C3 convertase via its interaction with C3b protein." in: The Journal of biological chemistry, Vol. 287, Issue 23, pp. 19528-36, (2012) (PubMed).Aliases for CFHR4 抗体
complement factor H related 4 (CFHR4) 抗体CFHL4 抗体
FHR-4 抗体
FHR4 抗体
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