This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008].
Young, Hopkins, Hay, Epton, Mills, Black, Gardner, Sullivan, Gamble: "Lung cancer susceptibility model based on age, family history and genetic variants." in: PLoS ONE, Vol. 4, Issue 4, pp. e5302, (2009) (PubMed).