Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1) 抗体
(Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1) (CHL1))
The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. This protein may also play a role in the growth of certain cancers. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Nov 2011].
Latest Publications for our Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1) 抗体
Huang, Zhu, Zhao, Wu, Wu, Schachner, Xiao, Fan: "CHL1 negatively regulates the proliferation and neuronal differentiation of neural progenitor cells through activation of the ERK1/2 MAPK pathway." in: Molecular and cellular neurosciences, Vol. 46, Issue 1, pp. 296-307, (2011) (PubMed).
Ye, Tan, Ponniah, Takeda, Wang, Schachner, Watanabe, Pallen, Xiao: "Neural recognition molecules CHL1 and NB-3 regulate apical dendrite orientation in the neocortex via PTP alpha." in: The EMBO journal, Vol. 27, Issue 1, pp. 188-200, (2008) (PubMed).
Aliases for Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1) 抗体