CD8B 抗体
(CD8b Molecule (CD8B))
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010].
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Latest Publications for our CD8B 抗体
: "Prenatal stress, anxiety and depression alter transcripts, proteins and pathways associated with immune responses at the maternal-fetal interface†." in: Biology of reproduction, Vol. 106, Issue 3, pp. 449-462, (2022) (PubMed).: "B lymphocytes play a limited role in clearance of Campylobacter jejuni from the chicken intestinal tract." in: Scientific reports, Vol. 7, pp. 45090, (2018) (PubMed).
: "Suppression of NK cells and regulatory T lymphocytes in cats naturally infected with feline infectious peritonitis virus." in: Veterinary microbiology, Vol. 164, Issue 1-2, pp. 46-59, (2013) (PubMed).
: "Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins." in: Journal of virology, Vol. 86, Issue 1, pp. 36-48, (2012) (PubMed).
: "In vitro assessment of the feline cell-mediated immune response against feline panleukopeniavirus, calicivirus and felid herpesvirus 1 using 5-bromo-2'-deoxyuridine labeling." in: Veterinary immunology and immunopathology, Vol. 146, Issue 2, pp. 177-84, (2012) (PubMed).
: "Natural killer cells: frequency, phenotype and function in healthy cats." in: Veterinary immunology and immunopathology, Vol. 150, Issue 1-2, pp. 69-78, (2012) (PubMed).
: "Flow cytometric assessment of chicken T cell-mediated immune responses after Newcastle disease virus vaccination and challenge." in: Vaccine, (2010) (PubMed).
: "Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells." in: Journal of translational medicine, Vol. 8, pp. 23, (2010) (PubMed).
: "Significant change in ZAP-70 expression during the course of chronic lymphocytic leukemia." in: European journal of haematology, Vol. 84, Issue 6, pp. 513-7, (2010) (PubMed).
: "Phenotyping, functional characterization, and developmental changes in canine intestinal intraepithelial lymphocytes." in: Veterinary research, Vol. 40, Issue 6, pp. 58, (2009) (PubMed).
Aliases for CD8B 抗体
CD8b molecule (Cd8b) 抗体CD8b molecule (CD8B) 抗体
CD8 antigen, beta chain 1 (Cd8b1) 抗体
Cd8b 抗体
CD8B1 抗体
Cd8b1 抗体
LEU2 抗体
Ly-3 抗体
Ly-C 抗体
LY3 抗体
Lyt-3 抗体
LYT3 抗体
P37 抗体
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