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CD133 产品

(Prominin 1 (PROM1))

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This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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Featured CD133 Categories

CD133 抗体

High quality antibodies with extensive validation data.

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Latest Publications for our CD133 Products

Bychkov, Kirichenko, Shulepko, Mikhaylova, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis." in: Biomedicines, Vol. 9, Issue 10, (2021) (PubMed).

Goričan, Gole, Potočnik: "Head and Neck Cancer Stem Cell-Enriched Spheroid Model for Anticancer Compound Screening." in: Cells, Vol. 9, Issue 7, (2020) (PubMed).

Trevellin, Pirozzolo, Fassan, Vettor: "Prognostic value of stem cell markers in esophageal and esophagogastric junction cancer: a meta-analysis." in: Journal of Cancer, Vol. 11, Issue 14, pp. 4240-4249, (2020) (PubMed).

Uygur, Leikina, Melikov, Villasmil, Verma, Vary, Chernomordik: "Interactions with Muscle Cells Boost Fusion, Stemness, and Drug Resistance of Prostate Cancer Cells." in: Molecular cancer research : MCR, Vol. 17, Issue 3, pp. 806-820, (2019) (PubMed).

Bhattacharyya, Mitra, Ray, Biswas, Banerjee, Majumder, Mustafi, Murmu: "Reversing effect of Lupeol on vasculogenic mimicry in murine melanoma progression." in: Microvascular research, Vol. 121, pp. 52-62, (2019) (PubMed).

Acosta, Lee, Nguyen, Kaneko, Borlongan: "Endothelial Progenitor Cells Modulate Inflammation-Associated Stroke Vasculome." in: Stem cell reviews, Vol. 15, Issue 2, pp. 256-275, (2019) (PubMed).

Fu, Zhou, Shi, Kang, Lu, Li, Li, Yu: "Spontaneous formation of tumor spheroid on a hydrophilic filter paper for cancer stem cell enrichment." in: Colloids and surfaces. B, Biointerfaces, Vol. 174, pp. 426-434, (2019) (PubMed).

Nargesi, Zhu, Conley, Woollard, Saadiq, Lerman, Eirin: "Renovascular disease induces mitochondrial damage in swine scattered tubular cells." in: American journal of physiology. Renal physiology, Vol. 317, Issue 5, pp. F1142-F1153, (2019) (PubMed).

Aghajani Nargesi, Zhu, Liu, Tang, Jordan, Lerman, Eirin: "Renal Artery Stenosis Alters Gene Expression in Swine Scattered Tubular-Like Cells." in: International journal of molecular sciences, Vol. 20, Issue 20, (2019) (PubMed).

Liu, Kim, Dong, Dong, Huang, Liu, Liangpunsakul, Dong: "Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 10, pp. 2685-2693, (2019) (PubMed).

Synonyms and alternative names related to CD133

prominin 1 (Prom1), prominin 1 (PROM1), 4932416E19Rik, AC133, CD133, CORD12, MCDR2, Prom, Prom-1, Proml1, PROML1, RP41, STGD4

Protein level used designations for CD133

  • prominin-1
  • prominin-like 1
  • antigen AC133 homolog
  • prominin-like protein 1
  • fudenine
  • antigen AC133
  • hProminin
  • hematopoietic stem cell antigen
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