CCR5 抗体
(Chemokine (C-C Motif) Receptor 5 (CCR5))
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Latest Publications for our CCR5 抗体
: "Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targets." in: BMC immunology, Vol. 17, Issue 1, pp. 7, (2016) (PubMed).
: "CIB1 and CIB2 are HIV-1 helper factors involved in viral entry." in: Scientific reports, Vol. 6, pp. 30927, (2016) (PubMed).
: "Structural Insights into the Inhibitory Mechanism of an Antibody against B7-H6, a Stress-Induced Cellular Ligand for the Natural Killer Cell Receptor NKp30." in: Journal of molecular biology, Vol. 428, Issue 22, pp. 4457-4466, (2016) (PubMed).
: "A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128381, (2015) (PubMed).
: "CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia." in: Blood, Vol. 125, Issue 13, pp. 2087-94, (2015) (PubMed).
: "The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer." in: British journal of cancer, Vol. 112, Issue 2, pp. 319-28, (2015) (PubMed).
: "CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines." in: Cancer research, Vol. 74, Issue 23, pp. 7103-14, (2014) (PubMed).
: "Chondrocyte-specific pathology during skeletal growth and therapeutics in a murine model of pseudoachondroplasia." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 29, Issue 5, pp. 1258-68, (2014) (PubMed).
: "Effects of the Chemokine Receptor 5 (CCR5)-Delta32 Mutation on Hepatitis C Virus-Specific Immune Responses and Liver Tissue Pathology in HCV Infected Patients." in: Hepatitis monthly, Vol. 14, Issue 7, pp. e11283, (2014) (PubMed).
: "CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association." in: PLoS ONE, Vol. 9, Issue 2, pp. e89056, (2014) (PubMed).
: "CIB1 and CIB2 are HIV-1 helper factors involved in viral entry." in: Scientific reports, Vol. 6, pp. 30927, (2016) (PubMed).
: "Structural Insights into the Inhibitory Mechanism of an Antibody against B7-H6, a Stress-Induced Cellular Ligand for the Natural Killer Cell Receptor NKp30." in: Journal of molecular biology, Vol. 428, Issue 22, pp. 4457-4466, (2016) (PubMed).
: "A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128381, (2015) (PubMed).
: "CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia." in: Blood, Vol. 125, Issue 13, pp. 2087-94, (2015) (PubMed).
: "The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer." in: British journal of cancer, Vol. 112, Issue 2, pp. 319-28, (2015) (PubMed).
: "CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines." in: Cancer research, Vol. 74, Issue 23, pp. 7103-14, (2014) (PubMed).
: "Chondrocyte-specific pathology during skeletal growth and therapeutics in a murine model of pseudoachondroplasia." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 29, Issue 5, pp. 1258-68, (2014) (PubMed).
: "Effects of the Chemokine Receptor 5 (CCR5)-Delta32 Mutation on Hepatitis C Virus-Specific Immune Responses and Liver Tissue Pathology in HCV Infected Patients." in: Hepatitis monthly, Vol. 14, Issue 7, pp. e11283, (2014) (PubMed).
: "CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association." in: PLoS ONE, Vol. 9, Issue 2, pp. e89056, (2014) (PubMed).
Aliases for CCR5 抗体
C-C motif chemokine receptor 5 (gene/pseudogene) (CCR5) 抗体chemokine (C-C motif) receptor 5 (Ccr5) 抗体
chemokine (C-C motif) receptor 5 (CCR5) 抗体
C-C motif chemokine receptor 5 (CCR5) 抗体
AM4-7 抗体
CC-CKR-5 抗体
CCCKR5 抗体
CCR-5 抗体
CCR1-L 抗体
CCR5 抗体
CD195 抗体
CKR-5 抗体
CKR5 抗体
Ckr5 抗体
CMKBR5 抗体
Cmkbr5 抗体
GPCR 抗体
IDDM22 抗体
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