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CCDC6 产品

(Coiled-Coil Domain Containing 6 (CCDC6))

Categories

This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.[provided by RefSeq, Sep 2010].

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Featured CCDC6 Categories

CCDC6 抗体

High quality antibodies with extensive validation data.

CCDC6 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CCDC6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC
Validations
  • (6)
Cat. No. ABIN7258894
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (4)
Cat. No. ABIN7148132
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN563526
Quantity 100 μg
Datasheet Datasheet

Recommended CCDC6 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6213283
Quantity 96 tests
Datasheet Datasheet

Recommended CCDC6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1348309
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348311
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN3091203
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CCDC6 Products

Luise, Merolla, Leone, Paladino, Sarnataro, Fusco, Celetti: "Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcriptional activity." in: PLoS ONE, Vol. 7, Issue 11, pp. e49298, (2012) (PubMed).

Leone, Mansueto, Pierantoni, Tornincasa, Merolla, Cerrato, Santoro, Grieco, Scaloni, Celetti, Fusco: "CCDC6 represses CREB1 activity by recruiting histone deacetylase 1 and protein phosphatase 1." in: Oncogene, Vol. 29, Issue 30, pp. 4341-51, (2010) (PubMed).

Richardson, Gujral, Peng, Asa, Mulligan: "Transcript level modulates the inherent oncogenicity of RET/PTC oncoproteins." in: Cancer research, Vol. 69, Issue 11, pp. 4861-9, (2009) (PubMed).

Jazdzewski, Murray, Franssila, Jarzab, Schoenberg, de la Chapelle: "Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 20, pp. 7269-74, (2008) (PubMed).

Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, (2007) (PubMed).

Synonyms and alternative names related to CCDC6

coiled-coil domain containing 6a (ccdc6a), coiled-coil domain containing 6 S homeolog (ccdc6.S), coiled-coil domain containing 6 (CCDC6), coiled-coil domain containing 6 (Ccdc6), 2810012H18Rik, AA536681, AA960498, AW061011, ccdc6, D10S170, fj36e04, H4, MGC53501, PTC, TPC, TST1, wu:fj36e04, zgc:56563, zgc:77435

Protein level used designations for CCDC6

  • coiled-coil domain-containing protein 6
  • coiled-coil domain containing 6
  • papillary thyroid carcinoma-encoded protein
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