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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase ELISA试剂盒

(Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB))
E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B- cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways. In naive T-cells, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production. Also acts by promoting PIK3R1/p85 ubiquitination, which impairs its recruitment to the TCR and subsequent activation. In activated T- cells, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy. In B-cells, acts by ubiquitinating SYK and promoting its proteasomal degradation. Slightly promotes SRC ubiquitination. May be involved in EGFR ubiquitination and internalization. May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3. {ECO:0000269|PubMed:10646608, ECO:0000269|PubMed:10646609, ECO:0000269|PubMed:11070165, ECO:0000269|PubMed:11526404, ECO:0000269|PubMed:12771181, ECO:0000269|PubMed:15308098}.
Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) ELISA 试剂盒 Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) ELISA 试剂盒 Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) ELISA 试剂盒 (ABIN6965529)

CBLB 适用: 人 Colorimetric Sandwich ELISA 78.125 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) ELISA 试剂盒 (ABIN6200984)

CBLB 适用: 大鼠 Colorimetric Sandwich ELISA Plasma, Serum

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Find Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase ELISA试剂盒 for a variety of species such as anti-Human Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase, anti-Mouse Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase, anti-Rat Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965529
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1131076
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6200984
Quantity 96 tests
Datasheet Datasheet

Aliases for Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase ELISA试剂盒

Cbl proto-oncogene B, E3 ubiquitin protein ligase S homeolog (cblb.S) ELISA试剂盒
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