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抗Human CAP1 抗体:
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Human Monoclonal CAP1 Primary Antibody for ELISA, WB - ABIN564567
Cauwe, Martens, Van den Steen, Proost, Van Aelst, Blockmans, Opdenakker: Adenylyl cyclase-associated protein-1/CAP1 as a biological target substrate of gelatinase B/MMP-9. in Experimental cell research 2008
Show all 2 Pubmed References
Human Polyclonal CAP1 Primary Antibody for FACS, IF - ABIN523895
Wakeel, Kuriakose, McBride: An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. in Infection and immunity 2009
Human Polyclonal CAP1 Primary Antibody for IF, IP - ABIN950065
Jansen, Collins, Golden, Sokolova, Goode: Structure and mechanism of mouse cyclase-associated protein (CAP1) in regulating actin dynamics. in The Journal of biological chemistry 2014
Significant up-regulation of PBMCs CAP1 (显示 PRSS8 抗体), CD36 (显示 CD36 抗体) mRNA and plasma resistin (显示 RETN 抗体) found in significant coronary artery disease, as well as in nonsignificant coronary artery disease compared to control group, indicates that resistin (显示 RETN 抗体) could be able to exert its effects stronger on cells with up-regulated CAP1 (显示 PRSS8 抗体) mRNA thus contributing atherosclerosis development.
REVIEW: summarizes information available to date about the structural organization, regulation of functional activity of adenylyl cyclase-associated protein 1 (CAP1), and its participation in cellular processes
Results identify a role for CAP1 (显示 PRSS8 抗体) in regulating proliferative transformation of cancer cells, with ERK (显示 EPHB2 抗体) signaling playing pivotal roles in mediating both cell functions.
CAP1 (显示 PRSS8 抗体) expression is markedly increased in human glioma and that downregulation of CAP1 (显示 PRSS8 抗体) in tumors may serve as a treatment for glioma patients.
our results indicated that CAP1 (显示 PRSS8 抗体) participated in the molecular pathological process of glioma
a high expression of CAP1 (显示 PRSS8 抗体) is involved in the pathogenesis of EOC, and that the downregulation of CAP1 (显示 PRSS8 抗体) in tumor cells may be a therapeutic target for the treatment of patients with EOC.
This study demonstrated an inverse relationship between CAP1 (显示 PRSS8 抗体) and MMP-9 (显示 MMP9 抗体) expression, high expression of MMP-9 (显示 MMP9 抗体) and low expression of CAP1 (显示 PRSS8 抗体) in those with chronic obstructive pulmonary disease compared with the non-chronic obstructive pulmonary disease group.
CAP1 (显示 PRSS8 抗体) is involved in the brain metastasis in non-small cell lung cancer.CAP1 overexpression is associated with poor prognosis in non-small cell lung cancer patients.
Overexpression of CAP1 (显示 PRSS8 抗体) in monocytes enhanced the resistin (显示 RETN 抗体)-induced increased activity of the cAMP-dependent signaling.
results indicate that upregulated expression of CAP1 (显示 PRSS8 抗体) might contribute heavily to the metastasis of hepatocellular carcinoma.
Phosphorylation regulates CAP1 function through association with cofilin and actin in order to control the actin cytoskeleton.
a novel inhibitory interaction between CAP1/Prss8 (显示 PRSS8 抗体) and nexin-1 (显示 SERPINE2 抗体), opening the search for specific CAP1/Prss8 (显示 PRSS8 抗体) antagonists that are independent of its catalytic activity
CAP1 depletion also led to changes in cofilin phosphorylation and localization as well as activation of focal adhesion kinase (FAK) and enhanced cell spreading.
study provides evidence that catalyzing nucleotide exchange on actin monomers via the beta-sheet domain is the most highly conserved function of CAPs (显示 CAPS 抗体) from mammals to apicomplexan parasites.
CAP1 is widely expressed in mouse nonmuscle cells and promotes cofilin-induced actin dynamics.
CAP1 shows a broad tissue distribution and localizes to the cytoplasm
Postsynaptic adenylyl cyclase 1 (显示 ADCY1 抗体) is required for functional maturation of thalamocortical synapses and morphological barrels.
These studies suggest that CAP1 provides a direct link from the actin cytoskeleton to the mitochondria by functioning as an actin shuttle.
cap1 regulates cortical actin distribution specifically in the anterior mesendoderm of the zebrafish gastrula.
The requirement of Cap1 for a cellular apical constriction step suggests a conservation of gene function for a cell biological event critical to many developmental processes.
Bovine herpesvirus 1 infection stimulates caspase 1 (显示 CASP1 抗体) activity.
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified.
, adenylyl cyclase-associated protein 1
, CAP, adenylate cyclase-associated protein 1 (yeast)
, adenylyl cyclase-associated protein
, CAP, adenylate cyclase-associated protein 1
, Adenylyl cyclase-associated protein 1
, adenylyl cyclase-associated CAP protein homolog 1 iae
, adenylyl cyclase-associated CAP protein, yeast homolog 1
, cyclase-associated protein homologue
, ASP-56 protein
, TNF receptor-associated factor 3
, adenylate cyclase associated protein 1