蛋白简介

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.

Alternative names and synonyms associated with AKAP5

• A kinase (PRKA) anchor protein 5 (AKAP5) 抗体
• A-kinase anchoring protein 5 (AKAP5) 抗体
• A kinase (PRKA) anchor protein 5 (Akap5) 抗体
• A-kinase anchoring protein 5 (Akap5) 抗体

• 3526401B18Rik 抗体
• AKAP 抗体
• AKAP-5 抗体
• AKAP5 抗体
• AKAP75 抗体
• 显示所有的同义词和别名
• Akap79 抗体
• AKAP 150 抗体
• AKAP150 抗体
• BB098886 抗体
• Gm258 抗体
• H21 抗体
• P75 抗体
• P150 抗体

Protein level used designations for AKAP5

A kinase (PRKA) anchor protein 5 , A-kinase anchor protein 5 , A-kinase anchor protein 5-like , a-kinase anchor protein 5-like , A-kinase anchor protein 79 kDa , A-kinase anchor protein, 79kDa , A-kinase anchoring protein 75/79 , AKAP 79 , AKAP-5 , cAMP-dependent protein kinase regulatory subunit II high affinity binding protein , cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein , A-kinase anchor protein 75 kDa , AKAP 75 , anchor protein regulatory subunit (AKAP75) , A-kinase anchor protein 150 kDa , AKAP 150 , RII-B-binding protein