This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
Li, Fu, Wang, Wang, Zeng, Shao: "Down-regulation of c9orf86 in human breast cancer cells inhibits cell proliferation, invasion and tumor growth and correlates with survival of breast cancer patients." in: PLoS ONE, Vol. 8, Issue 8, pp. e71764, (2013) (PubMed).
Aliases for C9orf86 抗体
RAB, member RAS oncogene family like 6 (rabl6) 抗体 RAB, member RAS oncogene family-like 6 (Rabl6) 抗体 RAB, member RAS oncogene family like 6 (RABL6) 抗体 B230208H17Rik 抗体 C9orf86 抗体 C11H9orf86 抗体 parf 抗体 PARF 抗体 pp8875 抗体 Rbel1 抗体 RBEL1 抗体 Rbel1a 抗体 Rbel1b 抗体