C5 抗体
(Complement Component 5 (C5))
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| C5 抗体 (AA 253-281) (FITC) | 人 | 兔 Polyclonal |
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| C5 抗体 (N-Term) | 人 | 小鼠 Monoclonal |
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| C5 抗体 | 人 | 小鼠 Monoclonal |
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| C5 抗体 | 人 | 小鼠 Monoclonal |
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| C5 抗体 | 人 | 小鼠 Monoclonal |
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| C5 抗体 (N-Term) | 人 | 小鼠 Monoclonal |
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| C5 抗体 | 人 | 小鼠 Monoclonal |
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| C5 抗体 | 大鼠 | 小鼠 Monoclonal |
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| C5 抗体 | 人 | 小鼠 Monoclonal |
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| C5 抗体 (AA 1-74) | Pig | 兔 Polyclonal |
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| C5 抗体 (AA 1-74) (HRP) | Pig | 兔 Polyclonal |
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| C5 抗体 (AA 1-74) (Biotin) | Pig | 兔 Polyclonal |
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| C5 抗体 (AA 1-74) (FITC) | Pig | 兔 Polyclonal |
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| Recombinant C5 抗体 | 人 | 小鼠 Monoclonal |
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| Recombinant C5 抗体 | 人 | 兔 Monoclonal |
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| C5 抗体 (AA 678-751) | 人 | 兔 Polyclonal |
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| C5 抗体 (AA 678-751) (HRP) | 人 | 兔 Polyclonal |
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| C5 抗体 (AA 678-751) (FITC) | 人 | 兔 Polyclonal |
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| C5 抗体 (AA 678-751) (Biotin) | 人 | 兔 Polyclonal |
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| C5 抗体 | 人 | 山羊 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 253-281
Primary Antibody
- ELISA (ELISA: 所列应用)
- Neut (Neutralization: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 561
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- Func (Functional Studies: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 046-10-2-2 (10-04)
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- N-Term
Primary Antibody
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- Pig
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-74
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- Pig
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 1-74
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- Pig
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 1-74
Primary Antibody
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 13H2
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG2a
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- A734
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
Primary Antibody
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 678-751
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 678-751
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 678-751
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 678-751
Latest Publications for our C5 抗体
: "SAK-HV Triggered a Short-period Lipid-lowering Biotherapy Based on the Energy Model of Liver Proliferation via a Novel Pathway." in: Theranostics, Vol. 7, Issue 6, pp. 1749-1769, (2018) (PubMed).
: "Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis." in: Science immunology, Vol. 2, Issue 7, (2017) (PubMed).
: "Pre-neutralization of C5a-mediated effects by the monoclonal antibody 137-26 reacting with the C5a moiety of native C5 without preventing C5 cleavage." in: Clinical and experimental immunology, Vol. 133, Issue 2, pp. 160-9, (2003) (PubMed).
: "Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation." in: Blood, Vol. 100, Issue 5, pp. 1869-77, (2002) (PubMed).
: "Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma." in: Nature immunology, Vol. 1, Issue 3, pp. 221-6, (2001) (PubMed).
: "Analysis of the C5a anaphylatoxin core domain using a C5a phage library selected on differentiated U937 cells." in: Molecular immunology, Vol. 36, Issue 2, pp. 145-52, (1999) (PubMed).
: "Epitope mapping of a C5a neutralizing mAb using a combined approach of phage display, synthetic peptides and site-directed mutagenesis." in: Immunotechnology : an international journal of immunological engineering, Vol. 2, Issue 2, pp. 115-26, (1997) (PubMed).
: "Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex." in: Scandinavian journal of immunology, Vol. 28, Issue 3, pp. 307-12, (1988) (PubMed).
: "Detection of native human complement components C3 and C5 and their primary activation peptides C3a and C5a (anaphylatoxic peptides) by ELISAs with monoclonal antibodies." in: Journal of immunological methods, Vol. 111, Issue 2, pp. 241-52, (1988) (PubMed).
: "Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis." in: Science immunology, Vol. 2, Issue 7, (2017) (PubMed).
: "Pre-neutralization of C5a-mediated effects by the monoclonal antibody 137-26 reacting with the C5a moiety of native C5 without preventing C5 cleavage." in: Clinical and experimental immunology, Vol. 133, Issue 2, pp. 160-9, (2003) (PubMed).
: "Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation." in: Blood, Vol. 100, Issue 5, pp. 1869-77, (2002) (PubMed).
: "Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma." in: Nature immunology, Vol. 1, Issue 3, pp. 221-6, (2001) (PubMed).
: "Analysis of the C5a anaphylatoxin core domain using a C5a phage library selected on differentiated U937 cells." in: Molecular immunology, Vol. 36, Issue 2, pp. 145-52, (1999) (PubMed).
: "Epitope mapping of a C5a neutralizing mAb using a combined approach of phage display, synthetic peptides and site-directed mutagenesis." in: Immunotechnology : an international journal of immunological engineering, Vol. 2, Issue 2, pp. 115-26, (1997) (PubMed).
: "Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex." in: Scandinavian journal of immunology, Vol. 28, Issue 3, pp. 307-12, (1988) (PubMed).
: "Detection of native human complement components C3 and C5 and their primary activation peptides C3a and C5a (anaphylatoxic peptides) by ELISAs with monoclonal antibodies." in: Journal of immunological methods, Vol. 111, Issue 2, pp. 241-52, (1988) (PubMed).
Aliases for C5 抗体
complement C5 (C5) 抗体complement component 5 (c5) 抗体
complement component 5 (C5) 抗体
hemolytic complement (Hc) 抗体
C5 抗体
C5a 抗体
C5b 抗体
CPAMD4 抗体
Hc 抗体
He 抗体
LOC565774 抗体
RGD1561905 抗体
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