CAND1 产品
(Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
Categories
Enhances transcription from various types of promoters. Regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. Prevents neddylation of CUL1 by physically blocking access to the neddylation site. Disrupts interactions between CUL1 and SKP1 and between CUL1 and F-box proteins (By similarity).
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Featured CAND1 Categories
CAND1 抗体
High quality antibodies with extensive validation data.
CAND1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CAND1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CAND1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (1)
- (6)
Cat. No.
ABIN565932
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (6)
Cat. No.
ABIN527718
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN565931
Quantity
50 μL
Datasheet
Datasheet
Recommended CAND1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1128116
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1128117
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1128118
Quantity
96 tests
Datasheet
Datasheet
Recommended CAND1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1347960
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3090253
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3135876
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CAND1 Products
: "CAND1 promotes PLK4-mediated centriole overduplication and is frequently disrupted in prostate cancer." in: Neoplasia (New York, N.Y.), Vol. 14, Issue 9, pp. 799-806, (2012) (PubMed).: "Structural basis for a reciprocal regulation between SCF and CSN." in: Cell reports, Vol. 2, Issue 3, pp. 616-27, (2012) (PubMed).
: "Living donor liver transplantation for hepatocellular carcinoma: a single-center experience in Taiwan." in: Transplantation, Vol. 85, Issue 3, pp. 398-406, (2008) (PubMed).
: "High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected nonsmall cell lung cancer." in: British journal of cancer, (2008) (PubMed).
: "AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis." in: Plant physiology, Vol. 135, Issue 2, pp. 1020-6, (2004) (PubMed).
: "Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation." in: The Plant cell, Vol. 16, Issue 7, pp. 1870-82, (2004) (PubMed).
: "NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases." in: Molecular cell, Vol. 10, Issue 6, pp. 1511-8, (2002) (PubMed).
Synonyms and alternative names related to CAND1
cullin associated and neddylation dissociated 1 (CAND1), cullin-associated and neddylation dissociated (CAND1), cullin-associated and neddylation-dissociated 1 (Cand1), cullin-associated and neddylation-dissociated 1 (cand1), cullin-associated and neddylation-dissociated 1 L homeolog (cand1.L), cullin-associated NEDD8-dissociated protein 1 (LOC100159824), cullin-associated NEDD8-dissociated protein 1 (LOC100177977), cullin associated and neddylation disassociated 1 (Cand1), cullin associated and neddylation dissociated 1 (Cand1), 2310038O07Rik, 6330512O03Rik, AI195005, AI846556, ATCAND1, cand2, cullin-associated and neddylation dissociated, CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1, D10Ertd516e, ETA2, fb78a05, HEMIVENATA, HVE, mKIAA0829, T8K22.14, T8K22_14, TIP120, Tip120, tip120, TIP120A, Tip120A, tip120a, Tp120a, wu:fb78a05, zgc:55729Protein level used designations for CAND1
- TBP interacting protein
- TBP-interacting protein 120A
- TBP-interacting protein of 120 kDa A
- cullin-associated NEDD8-dissociated protein 1
- cullin-associated and neddylation-dissociated protein 1
- p120 CAND1
- TBP-interacting protein TIP120A
- cullin associated and neddylation disassociated 1
- cullin-associated and neddylation-dissociated 1
- TIP120 protein
- cullin-associated NEDD8-dissociated protein 1-like
- cullin-associated and neddylation-dissociated 2 (putative)
- TBP-interacting protein
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