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Calsyntenin 1 蛋白

(Calsyntenin 1 (CLSTN1))
Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2- mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1- binding. May modulate calcium-mediated postsynaptic signals (By similarity).

2 results :

CLSTN1 宿主: 人 宿主: 小麦胚 Recombinant AA, AP, ELISA, WB
产品编号 ABIN1349745
 
CLSTN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713079
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • ELISA
    • Standard (STD)
    • Western Blotting (WB)
  • 适用
    • Human
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Wheat germ
  • 抗原表位
    • AA 1-971
    • Transcript Variant 1
  • 标记
    • GST tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Supplier
    • OriGene
    • antibodies-online

Aliases for Calsyntenin 1 蛋白

calsyntenin 1 (CLSTN1) 蛋白
calsyntenin 1 (clstn1) 蛋白
calsyntenin 3 (clstn3) 蛋白
beta-catenin-interacting protein 1 (LOC100356725) 蛋白
calsyntenin-1 (LOC100435584) 蛋白
calsyntenin 1 (Clstn1) 蛋白
beta-catenin-interacting protein 1 (LOC479600) 蛋白
1810034E21Rik 蛋白
ALC-ALPHA 蛋白
alcalpha1 蛋白
alcalpha2 蛋白
CALSYNTENIN-1 蛋白
CDHR12 蛋白
clstn1 蛋白
Cst-1 蛋白
Cstn1 蛋白
CSTN1 蛋白
fm67g03 蛋白
PIK3CD 蛋白
wu:fk52g02 蛋白
wu:fm67g03 蛋白
XB31alpha 蛋白
zgc:56528 蛋白
zgc:153744 蛋白
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