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Calsyntenin 1 ELISA试剂盒

(Calsyntenin 1 (CLSTN1))
Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2- mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1- binding. May modulate calcium-mediated postsynaptic signals (By similarity).

1 results :

CLSTN1 适用: 人 Colorimetric Sandwich ELISA Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Lysate
产品编号 ABIN4882387
 
  • 类型 Kit
    • Kit
  • 应用范围 ELISA
    • ELISA
  • 适用
    • Human
  • 实验类型
    • Sandwich ELISA
  • Analytical Method
    • Quantitative
  • 检测方法
    • Colorimetric
  • Plate
    • Pre-coated
  • 标记
    • 非结合性
  • 样本
    • Cell Culture Supernatant
    • Cell Lysate
    • Plasma
    • Serum
    • Tissue Lysate
  • Supplier
    • RayBiotech

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