This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008].
Coughlin: "How the protease thrombin talks to cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 20, pp. 11023-7, (1999) (PubMed).
Niclou, Suidan, Brown-Luedi, Monard: "Expression of the thrombin receptor mRNA in rat brain." in: Cellular and molecular biology (Noisy-le-Grand, France), Vol. 40, Issue 3, pp. 421-8, (1994) (PubMed).
Nelken, Soifer, OKeefe, Vu, Charo, Coughlin: "Thrombin receptor expression in normal and atherosclerotic human arteries." in: The Journal of clinical investigation, Vol. 90, Issue 4, pp. 1614-21, (1992) (PubMed).
Aliases for CAB39L 抗体
calcium binding protein 39 like (CAB39L) 抗体 calcium binding protein 39-like (Cab39l) 抗体 calcium binding protein 39 like L homeolog (cab39l.L) 抗体 calcium binding protein 39-like (cab39l) 抗体 calcium binding protein 39 like (cab39l) 抗体 calcium-binding protein 39-like (LOC100369193) 抗体 SET domain bifurcated 2 (SETDB2) 抗体 calcium binding protein 39 like (Cab39l) 抗体 1500031K13Rik 抗体 2810425O13Rik 抗体 4930520C08Rik 抗体 AA589432 抗体 bA103J18.3 抗体 CAB39L 抗体 cab39l 抗体 MGC68674 抗体 MO2L 抗体 MO25-BETA 抗体 wu:fc52g02 抗体 zgc:92575 抗体