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CA12 产品

(Carbonic Anhydrase 12 (CA12))

Categories

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured CA12 Categories

CA12 抗体

High quality antibodies with extensive validation data.

CA12 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CA12 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CA12 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7437902
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (4)
Cat. No. ABIN513932
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (1)
  • (1)
Cat. No. ABIN1858202
Quantity 100 μL
Datasheet Datasheet

Recommended CA12 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954243
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882028
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730426
Quantity 96 tests
Datasheet Datasheet

Recommended CA12 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274033
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274032
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347761
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CA12 Products

Lee, Vecchio-Pagán, Sharma, Waheed, Li, Raraigh, Robbins, Han, Franca, Pellicore, Evans, Arcara, Nguyen, Luan, Belchis, Hertecant, Zabner, Sly, Cutting: "Loss of carbonic anhydrase XII function in individuals with elevated sweat chloride concentration and pulmonary airway disease." in: Human molecular genetics, Vol. 25, Issue 10, pp. 1923-1933, (2016) (PubMed).

Liu, Jing, Guo: "Clinical impact and reliability of carbonic anhydrase XII in the differentiation of malignant and tuberculous pleural effusions." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 1, pp. 351-4, (2013) (PubMed).

Vermeulen, Kornegoor, van der Wall, van der Groep, van Diest: "Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer." in: PLoS ONE, Vol. 8, Issue 1, pp. e53353, (2013) (PubMed).

Tafreshi, Bui, Bishop, Lloyd, Enkemann, Lopez, Abrahams, Carter, Vagner, Grobmyer, Gobmyer, Gillies, Morse: "Noninvasive detection of breast cancer lymph node metastasis using carbonic anhydrases IX and XII targeted imaging probes." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 1, pp. 207-19, (2012) (PubMed).

Vermeulen, van Brussel, van der Groep, Morsink, Bult, van der Wall, van Diest: "Immunophenotyping invasive breast cancer: paving the road for molecular imaging." in: BMC cancer, Vol. 12, pp. 240, (2012) (PubMed).

Lecoeur, Goossens, Vaccher, Bonte, Foulon: "A multivariate approach for the determination of isoelectric point of human carbonic anhydrase isoforms by capillary isoelectric focusing." in: Electrophoresis, Vol. 32, Issue 20, pp. 2857-66, (2011) (PubMed).

Davidson, Stavnes, Holth, Chen, Yang, Shih, Wang: "Gene expression signatures differentiate ovarian/peritoneal serous carcinoma from breast carcinoma in effusions." in: Journal of cellular and molecular medicine, Vol. 15, Issue 3, pp. 535-44, (2011) (PubMed).

Synonyms and alternative names related to CA12

carbonic anhydrase 12 (CA12), carbonic anhydrase 12 (Car12), carbonic anhydrase XII L homeolog (ca12.L), 2310047E01Rik, AI314958, Ca12, ca12, CAR12, CAXII, HsT18816

Protein level used designations for CA12

  • CA-XII
  • carbonate dehydratase XII
  • carbonic anhydrase 12
  • carbonic dehydratase
  • tumor antigen HOM-RCC-3.1.3
  • CA XII
  • carbonic anhydrase XII
  • carbonic anyhydrase 12
  • membrane-bound carbonic anhydrase 12
  • carbonic anhydrase XII L homeolog
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