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BRISC and BRCA1 A Complex Member 1 ELISA试剂盒

(BRISC and BRCA1 A Complex Member 1 (BABAM1))
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36. component (By similarity).

4 results

产品编号 ABIN1124171
 
产品编号 ABIN1124172
 
产品编号 ABIN1124173
 
产品编号 ABIN1124170
 
  • 类型 Kit
    • Kit
  • 应用范围 ELISA
    • ELISA
  • 适用
    • Cow
    • Human
    • Mouse
    • Rat
  • 检测方法
    • Colorimetric
  • Plate
    • Pre-coated
  • 标记
    • 非结合性
  • Supplier
    • EIAab

Aliases for BRISC and BRCA1 A Complex Member 1 ELISA试剂盒

BRISC and BRCA1 A complex member 1 (babam1) ELISA试剂盒
BRISC and BRCA1 A complex member 1 (BABAM1) ELISA试剂盒
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