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BRCA2 抗体

(Breast Cancer 2, Early Onset (BRCA2))
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008].

50 results

BRCA2 适用: 人, 大鼠, 小鼠 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN6888182
 
BRCA2 适用: 人, 大鼠, 小鼠 宿主: 兔 Polyclonal Biotin
产品编号 ABIN6872119
 
BRCA2 适用: 人, 大鼠, 小鼠 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN6815803
 
BRCA2 适用: 人, 大鼠, 小鼠 宿主: 兔 Polyclonal Alexa Fluor 750
产品编号 ABIN6856056
 
BRCA2 适用: 人, 大鼠, 小鼠 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN6831866
 
BRCA2 适用: 人, 大鼠, 小鼠 宿主: 兔 Polyclonal Alexa Fluor 647
产品编号 ABIN6847929
 
BRCA2 适用: 斑马鱼 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7613011
 
BRCA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F4 unconjugated
产品编号 ABIN2212063
 
BRCA2 适用: 人 WB, IHC, IP, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6331308
 
BRCA2 适用: 人 WB, IC 宿主: 小鼠 Monoclonal 5H4 unconjugated
产品编号 ABIN2212043
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunochromatography (IC)
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Rat
    • Mouse
    • Zebrafish (Danio rerio)
    • Monkey
    • Cat
    • Dog
    • Horse
  • 图像
  • 独立验证
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 1643CT739-91-87
    • 3D12
    • 3F4
    • 5F6
    • 5H4
    • F2H5
    • P-CS-4
  • 抗原表位
    • pSer3291
    • N-Term
    • AA 2737-2874
    • AA 2308-2537
    • AA 2913-3151
    • AA 2990-3232
    • AA 1-300
    • AA 2-109
    • AA 21-130
    • AA 2336-2478
    • AA 251-495
    • AA 2587-2601
    • AA 2850-2900
    • AA 2959-3418
    • AA 31-80
    • AA 3230-3310
    • AA 3319-3418
    • AA 450-500
    • C-Term
  • 标记
    • 非结合性
    • Biotin
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • FITC
    • HRP
  • 抗体亚型
    • IgG
    • IgG1
    • IgG1 kappa
    • IgG2a kappa
    • IgG3
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Signalway
    • Biomatik
    • Acris
    • Cohesion Biosciences
    • USBio
    • Abbexa
    • Assay Biotechnology Company, Inc.
    • Cloud-Clone
    • Covalab
    • OriGene

Latest Publications for our BRCA2 抗体

Whelan, Lee, Yin, Ofri, Bermudez-Hernandez, Keegan, Fenyo, Rothenberg: "Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks." in: Nature communications, Vol. 9, Issue 1, pp. 3882, (2019) (PubMed).

Chang, Zhang, Chang, Song, Qin, Chang, Guo, Wei: "Expression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancer." in: Oncology letters, Vol. 9, Issue 1, pp. 430-436, (2015) (PubMed).

Moeller, Yordy, Williams, Giri, Raju, Molkentine, Byers, Heymach, Story, Lee, Sturgis, Weber, Garden, Ang, Schwartz: "DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 7, pp. 2035-43, (2011) (PubMed).

Bernard-Gallon, Dechelotte, Le Corre, Chalabi, Vissac-Sabatier, Bignon: "Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia." in: Anticancer research, Vol. 24, Issue 1, pp. 321-4, (2004) (PubMed).

Bernard-Gallon, Déchelotte, Vissac, Aunoble, Cravello, Malpuech, Bignon: "BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite." in: Breast cancer research : BCR, Vol. 3, Issue 1, pp. 61-5, (2001) (PubMed).

Wu, Jiang, Thangaraju, Wu, Couch: "Induction of the BRCA2 promoter by nuclear factor-kappa B." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35548-56, (2000) (PubMed).

Sergeeva, Ershova, Veiko, Malinovskaya, Kalyanov, Kameneva, Stukalov, Dolgikh, Konkova, Ermakov, Veiko, Izhevskaya, Kutsev, Kostyuk: "Low-Dose Ionizing Radiation Affects Mesenchymal Stem Cells via Extracellular Oxidized Cell-Free DNA: A Possible Mediator of Bystander Effect and Adaptive Response." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 9515809 (PubMed).

Aliases for BRCA2 抗体

BRCA2, DNA repair associated (BRCA2) 抗体
Breast cancer 2, early onset homolog (Brca2) 抗体
BRCA2, DNA repair associated (Brca2) 抗体
breast cancer 2, early onset (brca2) 抗体
breast cancer 2, early onset (LOC584780) 抗体
BRCA2, DNA repair associated (brca2) 抗体
breast cancer 2, early onset (Brca2) 抗体
30169 抗体
AI256696 抗体
AW045498 抗体
BcDNA:SD25109 抗体
brca2 抗体
BRCA2 抗体
BRCC2 抗体
brcc2 抗体
BROVCA2 抗体
brovca2 抗体
CG13583 抗体
CG13584 抗体
CG30169 抗体
dmbrca2 抗体
Dmel\\CG30169 抗体
FACD 抗体
facd 抗体
FAD 抗体
fad 抗体
FAD1 抗体
fad1 抗体
FANCB 抗体
fancb 抗体
FANCD 抗体
FANCD1 抗体
fancd1 抗体
Fancd1 抗体
GLM3 抗体
PNCA2 抗体
RAB163 抗体
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