This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. [provided by RefSeq, Jul 2008].
Wang, Xue, Zhao, Liu, Ma, Ma: "Form-deprivation myopia induces decreased expression of bone morphogenetic protein-2, 5 in guinea pig sclera." in: International journal of ophthalmology, Vol. 8, Issue 1, pp. 39-45, (2015) (PubMed).
Wu, Chen, Mi, Chen, Wang, Gao: "Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients." in: International journal of clinical and experimental pathology, Vol. 7, Issue 2, pp. 529-36, (2014) (PubMed).
Xu, Shiba, Mizuno, Uchida, Mouri, Kawaguchi, Kurihara: "Effect of bone morphogenetic proteins-4, -5 and -6 on DNA synthesis and expression of bone-related proteins in cultured human periodontal ligament cells." in: Cell biology international, Vol. 28, Issue 10, pp. 675-82, (2004) (PubMed).
Luo, Dunn, Ewing, Sauvageot, Chen, Trent, Isaacs: "Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis." in: The Prostate, Vol. 51, Issue 3, pp. 189-200, (2002) (PubMed).
Jin, Lu, Liong, Lau, Tipoe: "Transcriptional mRNA of BMP-2, 3, 4 and 5 in trigeminal nerve, benign and malignant peripheral nerve sheath tumors." in: Histology and histopathology, Vol. 16, Issue 4, pp. 1013-9, (2001) (PubMed).
Aliases for BMP5 抗体
bone morphogenetic protein 5 (bmp5) 抗体 bone morphogenetic protein 5 (BMP5) 抗体 bone morphogenetic protein 5 (LOC100539495) 抗体 bone morphogenetic protein 5 (Bmp5) 抗体 AU023399 抗体 BMP5 抗体 bmp5l 抗体 hm:zehl0669 抗体 se 抗体 zehl0669 抗体 zgc:64230 抗体