beta Arrestin 1 抗体
(Arrestin, beta 1 (ARRB1))
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011].
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Latest Publications for our beta Arrestin 1 抗体
: "G protein-coupled receptor kinases promote phosphorylation and beta-arrestin-mediated internalization of CCR5 homo- and hetero-oligomers." in: The Journal of biological chemistry, Vol. 280, Issue 45, pp. 37503-15, (2005) (PubMed).: "Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6272-85, (2002) (PubMed).
: "beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport." in: The Journal of biological chemistry, Vol. 276, Issue 47, pp. 43663-7, (2001) (PubMed).
: "beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2." in: The Journal of cell biology, Vol. 148, Issue 6, pp. 1267-81, (2000) (PubMed).
: "Arrestin interactions with G protein-coupled receptors. Direct binding studies of wild type and mutant arrestins with rhodopsin, beta 2-adrenergic, and m2 muscarinic cholinergic receptors." in: The Journal of biological chemistry, Vol. 270, Issue 2, pp. 720-31, (1995) (PubMed).
: "Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family." in: The Journal of biological chemistry, Vol. 267, Issue 25, pp. 17882-90, (1992) (PubMed).
Aliases for beta Arrestin 1 抗体
arrestin beta 1 (ARRB1) 抗体arrestin, beta 1 (arrb1) 抗体
arrestin beta 1 L homeolog (arrb1.L) 抗体
beta-arrestin 1 (CpipJ_CPIJ016988) 抗体
beta-arrestin 1 (CpipJ_CPIJ017114) 抗体
putative beta-arrestin 1 (Smp_122900) 抗体
putative beta-arrestin 1 (Smp_126080) 抗体
putative beta-arrestin 1 (Smp_176980) 抗体
putative beta-arrestin 1 (Smp_152290) 抗体
arrestin, beta 1 (Arrb1) 抗体
arrestin beta 1 (Arrb1) 抗体
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betaarr1 抗体
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