This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
Chang, Olson, Schwartz: "Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy." in: Nutrition & metabolism, Vol. 10, Issue 1, pp. 47, (2013) (PubMed).
Xu, Huang, Xu, Qian, Zhu, Yan, Cai, Zhang, Xiao, Qu, Liu, Huang, Cheng, Li, Du, Hu, Shen, Lu, Fu, Zhong, Xu, Gu, Huang, Zhao, Hu, Gu, Chen, Han: "Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 26, pp. 15089-94, (2001) (PubMed).
Loeb-Hennard, McIntyre: "(R)-3-hydroxybutyrate dehydrogenase: selective phosphatidylcholine binding by the C-terminal domain." in: Biochemistry, Vol. 39, Issue 39, pp. 11928-38, (2000) (PubMed).
Aliases for BDH1 抗体
3-hydroxybutyrate dehydrogenase 1 (BDH1) 抗体 3-hydroxybutyrate dehydrogenase 1 S homeolog (bdh1.S) 抗体 3-hydroxybutyrate dehydrogenase, type 1 (bdh1) 抗体 3-hydroxybutyrate dehydrogenase, type 1 (BDH1) 抗体 3-hydroxybutyrate dehydrogenase, type 1 (Bdh1) 抗体 3-hydroxybutyrate dehydrogenase 1 (Bdh1) 抗体 3-hydroxybutyrate dehydrogenase, type 1 A (BDH1A) 抗体 2310032J20Rik 抗体 AI327223 抗体 BDH 抗体 Bdh 抗体 SDR9C1 抗体 zgc:163053 抗体