ATIC 抗体
(5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009].
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Latest Publications for our ATIC 抗体
: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." in: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).: "5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase." in: The Journal of biological chemistry, Vol. 280, Issue 47, pp. 39582-93, (2005) (PubMed).
: "AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC." in: American journal of human genetics, Vol. 74, Issue 6, pp. 1276-81, (2004) (PubMed).
: "The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate ..." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22168-74, (2002) (PubMed).
Aliases for ATIC 抗体
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog (atic.L) 抗体bifunctional purine biosynthesis protein PurH (purH) 抗体
bifunctional purine biosynthesis protein purH (purH) 抗体
Bifunctional purine biosynthesis protein purH (purH) 抗体
Bifunctional purine biosynthesis protein PurH (purH) 抗体
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) 抗体
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (Atic) 抗体
2610509C24Rik 抗体
AA536954 抗体
AICAR 抗体
AICARFT 抗体
AW212393 抗体
IMPCHASE 抗体
PURH 抗体
purH 抗体
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