ASTL 蛋白
(Astacin-Like Metallo-Endopeptidase (M12 Family) (ASTL))
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity).
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3 results
Aliases for ASTL 蛋白
astacin like metalloendopeptidase (ASTL) 蛋白astacin-like metalloendopeptidase (M12 family) (Astl) 蛋白
7420700F21 蛋白
C87576 蛋白
Sas1b 蛋白
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