ASB2 抗体
(Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].
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Latest Publications for our ASB2 抗体
: "Impaired dendritic-cell function in ectodermal dysplasia with immune deficiency is linked to defective NEMO ubiquitination." in: Blood, Vol. 108, Issue 7, pp. 2324-31, (2006) (PubMed).Aliases for ASB2 抗体
ankyrin repeat and SOCS box containing 2 (ASB2) 抗体ankyrin repeat and SOCS box-containing 2 (Asb2) 抗体
ankyrin repeat and SOCS box containing 2 (Asb2) 抗体
ankyrin repeat and SOCS box containing 2b (asb2b) 抗体
1110008E15Rik 抗体
ASB-2 抗体
ASB2 抗体
asb2 抗体
zgc:77223 抗体
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